Synthesis of potential antiviral compounds through C-H bond functionalizations

• Grant number: 25/21709-5
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate (Direct)
• Start date: March 01, 2026
• End date: February 28, 2027
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Emílio Carlos de Lucca Júnior
• Grantee: Milena Cristina Vieira Fernandes
• Supervisor: Lubin-Germain
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: CY Cergy Paris Université, France
• Associated to the scholarship: 21/07167-4 - On the search of a new catalysts for oxidation reactions of C-H bonds, BP.DD

Abstract

The integration of C-H bond functionalization into retrosynthetic analysis facilitates access to a wider array of molecular structures that, through conventional synthetic methods, may prove challenging to achieve or could require extensive synthetic pathways. In this context, the objective of this internship project is the application of C-H bond oxidation in the synthesis of nucleoside analogs, which offers a substantial opportunity for the discovery and development of new pharmacological agents.