Study about the level of FGF21 on liver and adipose tissue after hepatic surgery i...
Effect of diazoxide on liver ischemia/reperfusion lesions: experimental study in rats
Grant number: | 10/12698-4 |
Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
Start date: | November 01, 2010 |
End date: | October 31, 2012 |
Field of knowledge: | Health Sciences - Medicine - Surgery |
Principal Investigator: | Gustavo Pereira Fraga |
Grantee: | Thiago Messias Zago |
Host Institution: | Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
Abstract The abdomen is often involved in blunt trauma and penetrating and the liver is a viscera, by its size and location, common local of injury. Despite advances in treatment of hepatic trauma mortality is still significant, ranging from 5-27% in some studies. In recent decades the non-operative treatment has become standard for the management of hemodynamically stable patients. This way studies that evaluate the indications, complications and mortality involved with this form of treatment are very important. This study aims to evaluate the profile of patients who suffered liver trauma seen in the last 20 years, observing the changes in diagnosis and treatment of injury and assess whether there was a change in the incidence of complications and deaths in such patients. By evaluating the profile of patients who suffered liver trauma in the last 20 years, this project aims to demonstrate that the non-operative treatment became the treatment of choice in the management of hepatic trauma in haemodynamically stable patients. The project aims also evidence that the non-operative treatment has fewer complications and involves a shorter hospitalization than surgical treatment. It will be a descriptive study of registered cases in the protocol of Surgery of Trauma, Department of Surgery, Faculty of Medical Sciences (FCM), State University of Campinas (UNICAMP). The research subjects are patients with liver injury treated in the period 1990-2009, excluding patients younger than 14 years (treated by the team of pediatrics and pediatric surgery), or patients operated in other service and sent later. (AU) | |
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