Quality of life of patients with oral and oropharyngeal cancer from the Clinical Genome Project

• Grant number: 06/01238-7
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: September 01, 2006
• End date: May 31, 2009
• Field of knowledge: Health Sciences - Dentistry - Social and Preventive Dentistry
• Principal Investigator: José Leopoldo Ferreira Antunes
• Grantee: Maria Gabriela Haye Biazevic
• Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Wellbeing and physiological, psychological and social rehabilitation of patients, as well as survival and eradication of disease, are critical objective of medical interventions. Therefore, registering the self report of quality of life may represent an important implement for the monitoring of disease and treatment. The current study aimed at assessing quality of life for a cohort of patients with mouth and oropharynx cancer participating of the Clinical Genome Project, and submitted to surgery at the Heliópolis Hospital in São Paulo, Brazil. This assessment will use a Portuguese version of a questionnaire already validated for this type of research at the international context. The study will try to identify differential levels of quality of life associated with socio-demographic characteristics of patients (gender, age, income, schooling, occupation status and housing conditions), their clinical conditions (localization and size of the tumor, regional metastasis affecting lymph nodes), and treatments performed (surgery, radiotherapy, chemotherapy). The study will appraise the questionnaire applicability (referring to acceptability and ease for fulfilling the answers by respondents), and its responsiveness (the ability to detect clinical changes that follow medical interventions). The longitudinal assessment will observe three stages: immediately before and immediately after the surgery, and six months after surgery or after post-surgical radiotherapy. This procedure is expected to provide relevant information for implementing routines for this type of assessment, for the trans-cultural evaluation of the questionnaire, and for the acknowledgement of factors and conditions modifying the prognosis of current choices of treatment.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

HAYE BIAZEVIC, MARIA GABRIELA; TOPORCOV, TATIANA NATASHA; FERREIRA ANTUNES, JOSE LEOPOLDO; BRAGA ROTUNDO, LIGIA DROVANDI; BRASILEIRO, ROSANA SARMENTO; DE CARVALHO, MARCOS BRASILINO; DE GOIS FILHO, JOSE FRANCISCO; KOWALSKI, LUIZ PAULO. Cumulative Coffee Consumption and Reduced Risk of Oral and Oropharyngeal Cancer. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, v. 63, n. 3, p. 350-356, 2011. (06/01238-7)

MARIA GABRIELA HAYE BIAZEVIC; JOSÉ LEOPOLDO FERREIRA ANTUNES; JANINA TOGNI; FABIANA PAULA DE ANDRADE; MARCOS BRASILINO DE CARVALHO; VICTOR WÜNSCH-FILHO. Survival and quality of life of patients with oral and oropharyngeal cancer at 1-year follow-up of tumor resection. Journal of Applied Oral Science, v. 18, n. 3, p. 279-284, 2010-06-00. (06/01238-7)