Risk model for mastitis postpartum: hematological and biochemical aspects

Author(s)

Kamila Reis Santos

• Document type: Master's Dissertation
• Press: São Paulo.
• Institution: Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD)
• Defense date: 2016-04-28

Examining board members

Alice Maria Melville Paiva Della Libera; Maiara Garcia Blagitz Azevedo; Fabio Celidonio Pogliani

• Advisor: Alice Maria Melville Paiva Della Libera

Abstract

Objective identify biochemical, hematological and immunological systemic and local, associated with Bovine Mastitis risk model, drying at the end of the transitional period of the subsequent lactation cows treated with antimicrobial and sealant to dry. 34 cows were used the Dutch race, divided into three groups: control group (GC; n = 13); antimicrobial Group (GA; n = 10) animals receiving antimicrobial intramamário; sealant Group (GS; n = 11), composed of animals that received intramamário sealant. Milk samples were collected and evaluated blood where blood count, neutrophil oxidative metabolism (NBT), immunoglobulins, biochemistry, and CMT, somatic cell count, microbológico isolation of colostrum and milk and milk immunoglobulins in the 60 days preceding childbirth (M1) on the day of delivery (M2), three, seven, 15, 21, 30 days postpartum (M3, M4, M5, M6 and M7). Data were analyzed by the software Stata using a logistic regression model. The variables were analyzed individually to check the meaning and then, in combination, to evaluate the effect of individual variables. In the first phase of the analysis, logistic model was used for each variable related to the clinical findings, with P values less than 0.20 were considered as a variable selected and passed to the next stage of analysis. In the final model, selected variables were used in the first phase to develop a multivariate logistic model in which the variables with P ≤ 0.05 were retained in the final model. It was possible to identify changes in the parameters, protein, albumin and Fibrinogen, serve as biomarkers associated with Bovine Mastitis. Specific metabolic changes and characteristics of the transitional period, blood parameters, overlapping the effect of drying employees and protocols, it is suggested that the systemic profile the periparto cow is associated with mastitis (AU)

• FAPESP's process: 14/06995-7 - Bovine mastitis in postpartum: evaluation of the immune response and the application of preventive measures
• Grantee: Kamila Reis Santos
• Support Opportunities: Scholarships in Brazil - Master