Reconstruction of bone defects with calcium phosphate ceramic or low-power laser

Author(s)

Rosane Vieira da Silva

• Document type: Doctoral Thesis
• Press: Campinas, SP.
• Institution: Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia
• Defense date: 2006-07-14

Examining board members

Jose Angelo Camilli; Paulo Henrique Ferreira Caria; Sergio Augusto Catanzaro Guimarães; Paulo Pinto Joazeiro; Gerson Eduardo Rocha Campos

• Advisor: Jose Angelo Camilli

Abstract

Procedures that allow the reconstruction and speed up the bone repair are of great clinical importance. Being thus, considering the advantages offered for the biomaterials as substitute to the autogenous bone graft and the positive effect of the low-power-laser in the process bone regeneration, the proposals of the present work had been to study the contribution of the low-power-laser in the process of reconstruction of bone defect treated with autogenous bone graft, as well as, to analyze "in vitro" and "in vivo" the efficiency of calcium phosphate ceramic as possible substitute to the autogenous bone graft. The result demonstrated that laser irradiation at the grafted site stimulated osteogenesis during the initial stages of the healing process in na skull defect and this effect was dose dependent. While this, the "in vivo" study of the bioceramic demonstrated that the implantation was so efficient how much autogenous graft in the bone reconstruction process. In the study "in vitro", the human osteoblast had presented' good interaction with ceramics, presenting bigger preference for the surfaces most irregular of the material (AU)