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| Author(s): |
Marcel Gambin Marques
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Araçatuba. 2017-06-13. |
| Institution: | Universidade Estadual Paulista (Unesp). Faculdade de Medicina Veterinária. Araçatuba |
| Defense date: | 2017-06-05 |
| Advisor: | Paulo Sérgio Patto dos Santos; Wagner Luis Ferreira |
| Abstract | |
Because of its attractive pharmacological characteristics, remifentanil is widely used in human medicine for sedation and anesthesia in critically ill patients, mainly in cardiovascular diseases. Most studies report that this opioid promotes satisfactory analgesia without significant hemodynamic changes, preserving systolic and diastolic function. However, other authors report that depending on the way it is used, remifentanil administration can decrease heart rate, cardiac output and blood pressure, resulting in hemodynamic instability. In veterinary medicine, there are few studies investigating the cardiovascular effects of remifentanil, limiting its safely in the clinical routine. As the increased longevity of dogs, there was a proportional increase in the number of critically ill patients, including patients with cardiovascular diseases, who required safe anesthetic protocols. Therefore, remifentanil may become an excellent option if it is shown to be safe from a cardiovascular point of view. To date, there are no reports using echocardiographic techniques to assess systolic and diastolic function in dogs treated with remifentanil. The aim of this experiment was to evaluate the effects of continuous infusion of remifentanil on left ventricular systolic and diastolic function in dogs anesthetized with propofol. (AU) | |
| FAPESP's process: | 15/01806-4 - Echocardiographic evaluation in dogs submitted to continuous infusion of propofol associated or not to remifentanil |
| Grantee: | Marcel Gambin Marques |
| Support Opportunities: | Scholarships in Brazil - Master |