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| Author(s): |
Márcia Izumi Sakamoto
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | Pirassununga. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Zootecnica e Engenharia de Alimentos (FZE/BT) |
| Defense date: | 2009-12-17 |
| Examining board members: |
Douglas Emygdio de Faria;
Jovanir Ines Muller Fernandes;
Otto Mack Junqueira;
Alice Eiko Murakami;
João Alberto Negrão
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| Advisor: | Douglas Emygdio de Faria |
| Abstract | |
Three experiments were carried out to evaluate the influence of glutamine and nucleotides in diets of broiler chickens, on performance, development and enzymatic activity of the intestinal mucosa. In the first experiment, was estimated the best levels of glutamine sources supplementation, isolated (L-Gln) or associated with glutamic acid (Aminogut®). According to results for performance characteristics and enzymatics activities (intestinal mucosa and pancreas), was observed best performance for birds supplemented with 1.5% of L-Gln and 3.0% of Aminogut®. In the second experiment, was determined the best supplementation period (1 to 7; 1 to 14 or 1 to 21 days of age) of levels of glutamine sources observed in the first experiment. The results of performance, enzymatics activities and small intestine morphometry (duodenum, jejunum and ileum), suggested that glutamine sources evaluated can be supplemented during the first seven days of age, providing an increase in the enzymatics digestives and pancreatic activities at the broiler chickens. In the third experiment, were evaluated the effects of three sources with action trophic (L-Gln, Aminogut® and nucleotides) associated with vaccination against coccidiosis on development of small intestine and immune responses of the broilers. It was observed negative effect of vaccination on performance and morphometry of intestinal mucosa, however, at the end of experimental period, the glutamine sources showed efficiency to recovery epithelial losses of intestinal mucosa of birds, which were challenged against coccidiosis. Therefore, the supplementation of the trophic sources can be a strategy for optimum development of broilers when submitted to vaccination stress, considering the economic viability by the productive segment. (AU) | |