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| Author(s): |
Camila Rodrigues Eckert
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) |
| Defense date: | 2006-10-27 |
| Examining board members: |
Josef Wilhelm Baader;
Maurício da Silva Baptista;
Lúcia Maria Conserva
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| Advisor: | Josef Wilhelm Baader |
| Abstract | |
In this work a systematic study on the antiradical activity of flavonoids was performed, using the assay luminol/hemin/H2O2 developed by our research group. With the objective to establish a structure activity relationship for flavonoids, a study on the antioxidant properties of several phenolic derivatives as model compounds was also performed, using luminol chemiluminescence. The results obtained with the model compounds from the luminol assay are compared to those obtained by an assay which utilizes the stable DPPH radical as probe. Furthermore, a phytochemical study, monitored by the antiradical activity, was performed on extracts of Baccharis. This study led to the identification of two active components in the ethyl acetate phase of Baccharis regnellii leafs and the determination of its antiradical activity. (AU) | |
| FAPESP's process: | 04/04270-3 - Determinacao da atividade antiradicalar de flavanoides e extratos de especies de baccharis atraves da reacao quimiluminescente do luminol. |
| Grantee: | Camila Rodrigues Eckert |
| Support Opportunities: | Scholarships in Brazil - Master |