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| Author(s): |
Paula Cristina Gasperazzo Turrini
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) |
| Defense date: | 2017-03-10 |
| Examining board members: |
Marie Anne van Sluys;
Inácio de Loiola Meirelles Junqueira de Azevedo;
Rodrigo da Silva Galhardo;
Marilis do Valle Marques;
Leandro Marcio Moreira
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| Advisor: | Marie Anne van Sluys |
| Abstract | |
Mobile elements are genomic components that trigger genetic variability and promote the diversity of the population against the stochasticity of the environment and therefore, significantly influence the evolution of the Bacteria group. We investigate the influence of mobile genetic elements on X. oryzae lineages under three different aspects in this thesis. First, we investigated the horizontal transfer event of a operon, acquired exclusively by Xoc, but absent in Xoo and phylogenetically close lineages. The importance of the production of the phytohormone GA4 by Xoc is indicated by its high prevalence in different populations, in a wide geographic distribution and in a large time period.We also address the influence of mobile genetic elements more comprehensively in the X. oryzae genome. We describe how transposable elements, represented by IS elements, are capable of interfering in a central system of bacterial metabolism, such as the DNA repair system. Finally, we describe a new element found in X. oryzae and we analyze its organization, distribution, phylogeny and its transcriptional level. We also speculate its function in the X. oryzae-host interaction. Our results reiterate the importance of transposable elements enriching genetic variability of populations and infers on their relevant role in the diversification of X. oryzae lineage. We describe the variability, explore the consequences resulting from the amplification of transposition elements in the X. oryzae species and we show the complexity of this variation at the population level. (AU) | |
| FAPESP's process: | 12/24954-0 - The influence of mobile genetic elements on Xanthomonas oryzae lineages |
| Grantee: | Paula Cristina Gasperazzo Turrini |
| Support Opportunities: | Scholarships in Brazil - Doctorate |