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| Author(s): |
Thaís Marilia Fillus
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Ribeirão Preto. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Odontologia de Ribeirão Preto (PCARP/BC) |
| Defense date: | 2018-02-05 |
| Examining board members: |
Regina Guenka Palma Dibb;
Marilia Afonso Rabelo Buzalaf;
Silmara Aparecida Milori Corona;
Cesar Penazzo Lepri
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| Advisor: | Regina Guenka Palma Dibb |
| Abstract | |
The aim of the present study was to evaluate the alterations on root dentin of permanent teeth from individuals submitted to different antineoplastic treatments after erosion (in situ), caries (in situ) and abrasion (in vitro).Teeth extracted from patients who underwent cancer treatments in the head and neck region (HNC) at Hospital das Clínicas de Ribeirão Preto or at Hospital do Câncer de Barretos were selected and divided into groups according to antineoplastic treatment: CO-control: teeth extracted from healthy patients; RTX- radiotherapy in the head and neck region; QTX - chemotherapy; QRT - chemoradiotherapy. All fragments of root dentin were randomly distributed among the volunteers of each stage. In the first phase, erosion was carried out in situ; in the second phase the carious process was performed on the dental substrates in situ and the third phase was performed the in vitro abrasion test by teeth-brushing machine. The quantitative response variables were: wear profile, step, number, area and perimeter of the dentinal tubules, surface roughness, volume loss and quantification of the demineralized tissue; and qualitatively was analyzed the surface morphology. For the erosive process, it was observed an increase in the number, diameter and area of the tubules for all groups, but only QRT presented greater structural loss with statistical difference in relation to the other groups (p <0.05). For the carious process, no treatment provided a quantitative alteration greater than the control (p> 0.05). However, morphologically, it was observed that the dentinal tissue submitted to QRT presented a surface more amorphous. For the abrasion, the RTX group presented higher structural loss and statistically different from the other groups (p <0.05), besides presenting, morphologically, a higher pattern of wear. It was concluded that the antineoplastic treatments changed the root dentin and affected the processes of erosion, caries and abrasion (AU) | |
| FAPESP's process: | 16/17334-7 - Influence of radiotherapy and chemotherapy in dental caries induction, erosion and abrasion to root dentin of permanent teeth |
| Grantee: | Thaís Marilia Fillus |
| Support Opportunities: | Scholarships in Brazil - Master |