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Identification and functional annotation of novel transcripts with altered expression in pancreatic cancer
Full text
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| Author(s): |
Omar Julio Sosa
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Instituto de Matemática e Estatística (IME/SBI) |
| Defense date: | 2019-02-27 |
| Examining board members: |
Eduardo Moraes Rego Reis;
Helena Paula Brentani;
Edna Teruko Kimura;
Ana Cristina Victorino Krepischi;
Israel Tojal da Silva
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| Advisor: | Eduardo Moraes Rego Reis; João Carlos Setubal |
| Abstract | |
In the present work, we applied a bioinformatic pipeline to process and analyse data from total RNA-seq strand-oriented generated in our laboratory from matched samples of tumor and non-tumor adjacent pancreatic tissue from 14 patients with the goal of generate a high resolution catalog of the composition and the alterations in the transcriptome of PDAC, including protein coding and non coding genes. (AU) | |
| FAPESP's process: | 13/13350-0 - Implementation of computational analyses to identify novel biomarkers for molecular diagnosis of pancreatic tumors using next generation sequencing data |
| Grantee: | Omar Julio Sosa |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |