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| Author(s): |
André Augusto Justo
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD) |
| Defense date: | 2022-08-19 |
| Examining board members: |
Silvia Renata Gaido Cortopassi;
Adriano Bonfim Carregaro;
Líria Queiroz Luz Hirano
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| Advisor: | Silvia Renata Gaido Cortopassi |
| Abstract | |
The inhalation anesthesia is recommended for anesthetic maintenance in sea turtles; however, the role of pure oxygen (100% fraction of inspired oxygen) on the prolonged anesthetic recoveries commonly reported in sea turtle anesthesia has been questioned. This study aimed to compare recovery times in sevoflurane-anesthetized green turtles (Chelonia mydas) receiving pure oxygen (FI100) or room air (FI21), and to evaluate the impact of both fractions on cardiorespiratory and blood gas variables. In a randomized, blinded and cross-over design, eleven turtles were anesthetized (FI100 or FI21; one-week interval). Following intravenous propofol (5 mg/kg) and endotracheal intubation, animals were mechanically ventilated with sevoflurane for 90min. Heart rate (HR), partial pressure of expired CO2 (P’ETCO2) and expired sevoflurane fractions (FE’SEVO) were analyzed every 10min, and pulse oximetry (SpO2) every 30min. The FE’SEVO was set at 3.5%. At 90min of anesthesia, sevoflurane delivery ceased and times to beak the bite block, first muscle movement, first attempt to extubate and extubation were registered. Venous blood gas analysis was performed at 10min before anesthesia induction (MBa), 90min during anesthesia (MAn) and immediately following extubation (MExt). Time to beak the bite block was the only recovery variable different between groups (FI100: 52 ± 14.57 min and FI21: 44.64 ± 14.42 min; p = 0.03). The SpO2 was higher in FI100 than in FI21 at all timepoints of analysis (p<0.01). The P’ETCO2 and HR did not vary between groups, though both reduced over time (p<0.05). Blood gases were not different between groups. The pH increased (p<0.001) and PvCO2 reduced (p<0.0001) in MAn and MExt compared to MBa in both groups. Pure oxygen does not influence time to recovery from anesthesia nor does it impair cardiorrespiratory variables in comparison to room air in sevoflurane- anesthetized green turtles. (AU) | |
| FAPESP's process: | 20/02439-3 - Determination of echocardiographic parameters in conscious or sevoflurane-anesthetized green turtles (Chelonia mydas) |
| Grantee: | André Augusto Justo |
| Support Opportunities: | Scholarships in Brazil - Master |