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| Author(s): |
Emilio Carlos de Lucca Júnior
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Campinas, SP. |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Instituto de Química |
| Defense date: | 2011-02-21 |
| Examining board members: |
Luiz Carlos Dias;
Teodoro Saul Kaufman;
Cláudio Francisco Tormena
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| Advisor: | Luiz Carlos Dias |
| Abstract | |
The aldol reactions involving boron enolates 71 (P = TBS, R = t-Bu), 72 (P = PMB, R = t-Bu) and 96 (P = TPS, R = t-Bu) led to the formation of aldol adducts with moderate to good levels of diastereoselectivity, favouring the 1,5-syn isomer. The aldol reactions involving boron enolates 90 (P = Tr, R = t-Bu), 91 (P = Tr, R = Me) and 97 (P = TPS, R = Me) led to the formation of aldol in a 50:50 mixture. The aldol reactions of boron enolate 131 (P = TBS, R = Ph3C) led to excellent levels of diastereoselectivity, favouring the 1,5-syn adduct (AU) | |
| FAPESP's process: | 08/07457-8 - Study of the beta substituent in aldol reactions of boron enolates generated from methylketones |
| Grantee: | Emílio Carlos de Lucca Júnior |
| Support Opportunities: | Scholarships in Brazil - Master |