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| Author(s): |
Thaís Sebastiana Porfida Ferreira
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD) |
| Defense date: | 2011-09-23 |
| Examining board members: |
Andrea Micke Moreno;
André Furugen Cesar de Andrade;
Tania Alén Coutinho;
Terezinha Knöbl;
Luciane Tieko Shinya Zucon
|
| Advisor: | Andrea Micke Moreno |
| Abstract | |
Pasteurella multocida is the causative agent of many diseases of economic importance in veterinary medicine and has been described as an agent a high zoonotic potential. In Brazil, contrary to what is observed in the international literature, information about the frequency of this agent in animals such as dogs, cats and rabbits are nonexistent. This study proposes isolate strains of Pasteurella multocida from dogs, cats and rabbits, evaluate the frequency of this agent in these animal species, characterize the isolates according to the capsular type, and genes encoding virulence factors through the reaction polymerase chain, evaluate the antimicrobial resistance profiles of isolates and characterize the samples by PFGE. We examined 640 animals, 191 cats, 309 dogs and 140 rabbits. Among the animals examined were positive 8.1% for the isolation of P. multocida, and 10.4% of cats, dogs 0.9% and 20.7% of the rabbits studied. Among the 93 selected strains 22.5% were susceptible to all drugs tested, 77.4% of strains were resistant to at least one drug were used and 5.3% showed resistance to three or more drugs. Through PFGE were observed 39 pulsotipos discriminatory index equal to 0.97. All genes encoding virulence factors were detected in at least one isolated, none of which was present in 100% of the strains evaluated. (AU) | |
| FAPESP's process: | 07/08592-3 - Isolation and characterization of P. multocida from cats and dogs |
| Grantee: | Thaís Sebastiana Porfida Ferreira |
| Support Opportunities: | Scholarships in Brazil - Doctorate |