Surveillance of antibacterial resistance among enterobacteriaceae from environmental water samples in São Paulo State, Brazil.

Author(s)

Livia de Carvalho Fontes

• Document type: Master's Dissertation
• Press: São Paulo.
• Institution: Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI)
• Defense date: 2012-03-16

Examining board members

Nilton Erbet Lincopan Huenuman; Ana Cristina Gales; Anna Sara Shafferman Levin

• Advisor: Nilton Erbet Lincopan Huenuman

Abstract

Enterobacteria are important agents of infection may contaminate aquatic environments polluted by anthropogenic activities, which may be important sites for the selection and spread of bacteria resistant to antibiotics (ATB) for use in human and veterinary medicine. The aim of this study was to monitor the spread of enterobacteria resistant to ATB in aquatic environments of the state of Sao Paulo. From 2009-2010, 135 Enterobacteriaceae resistant to at least one ATB, were isolated from rivers, dams and sewage treatment plants. The phenotype resistant (MDR) was predominant in 64% of the isolates, and there was the predominance of E. coli (80%) and K pneumoniae (48%). Eight percent of the isolates showed ESBL phenotype (cefotaxime, MIC50 <font face=\"Symbol\">&#8805; 64 <font face=\"Symbol\">mg/ml) due to the presence of blaCTX-M-like, while the presence qnr-like gene was confirmed in 7% of isolates resistant to (ciprofloxacin MIC50 <font face=\"Symbol\">&#8805; 32<font face=\"Symbol\">mg/ml). Molecular typing revealed no clonal relationship among isolates of K. pneumoniae and E. coli. (AU)

• FAPESP's process: 10/04476-1 - Monitoring the presence of multidrug-resistant Enterobacteriaceae in enviromental water samples in São Paulo state, Brazil
• Grantee: Lívia de Carvalho Fontes
• Support Opportunities: Scholarships in Brazil - Master