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Patients health-related quality of life, depression and sense of coherence before myocardial revascularization and six months after it.

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Author(s):
Cristiane Franca Lisboa Gois
Total Authors: 1
Document type: Doctoral Thesis
Press: Ribeirão Preto.
Institution: Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (PCARP/BC)
Defense date:
Examining board members:
Rosana Aparecida Spadoti Dantas; Claudia Benedita dos Santos; Manoel Antonio dos Santos; Namie Okino Sawada; Andre Schmidt
Advisor: Rosana Aparecida Spadoti Dantas
Field of knowledge: Health Sciences - Nursing
Indexed in: Banco de Dados Bibliográficos da USP-DEDALUS; Biblioteca Digital de Teses e Dissertações - USP
Location: Universidade de São Paulo. Biblioteca Central do Campus de Ribeirão Preto
Abstract

The myocardial revascularization surgery (MRS) is a recommended procedure for patients who suffer from angina pectoris which is not controlled under clinical treatment and for patients who have an elevated degree of obstruction of the main coronary arteries. The surgery aims at improving patients health-related quality of life, alleviating the symptoms of the angina and increasing their survival period, particularly of those at greater risk. As to the coronaropathy in patients, depression has been related to a predictor for worse HRQL, whereas the sense of coherence (SC) has been associated with a better HRQL and lower depression. Objectives: To evaluate the HRQL, depression and SC before MRS and six months after it and to investigate the associations among these variables. Casuistics and method: A prospective and observational study, which was carried out at a hospital school in the countryside of the State of São Paulo and developed between September 2006 and April 2008. The sample was constituted of 54 patients who took part in the two evaluations. Three instruments of measurement were utilized: to evaluate HRQL, the Medical Outcomes Study 36 - item Short-Form (SF-36), towards depression, the Beck Depression Inventary (BDI) and regarding SC, the Questionnaire of Sense of Coherence by Antonovsky of 29 items (QSCA). The data were collected by means of interviews. Later, they were summarized through descriptive statistics and analysed by our using the test of correlation by Peterson and the t test. The analysis of hierarchical regression was carried out to verify the associations among the depression, six months after the surgery, sex, age, pre-operatory depression and SC, which were shown to be statistically significant in the bivariate analyses. The adopted level of significance was 0,05. Results: The participants were predominantly male, married and had a low level of instruction. The averages obtained, in the eight domains of SF-36, were higher in the second evaluation when compared to the preoperatory period, being such differences statistically significant. The measurement of depression was higher before than after the surgery (p=0,01) and there was no alteration in the measurement of SC (p=0,51). In the pre-operatory period, women presented a lower evaluation of HRQL in the components of SF-36, except towards Emotional aspects (p=0,68). Age presented moderate and positive correlation towards the General state of health (r=0,342, p=0,01) and with the SC (r=314, p=0,02), whereas a moderate and negative one regarding the measurement of depression (r= -0,307, p=0,02). After six months, men showed a better evaluation in all the components of SF-36, being such a difference statistically significant towards Physical aspects (p=0,04), Pain (p=0,02), General state of health (p=0,01) and Vitality (p=0,04). Age demonstrated to have a strong and positive correlation with the General state of health (r=570, p=0,00) and a moderate one with Mental health (r=0,388, p=0,00). To test if the presence of depression, six months after the surgery, was associated with the existent pre-operatory depression, as well as with the variables sex and age, hierarchical linear regression was carried out whose result revealed that 49% of the variance of the measurement of depression, six months after the surgery, was explained by such variables. With the inclusion of SC measurement in the model, it was stated that this variable explained 18,7% of the variance of the measurement of depression by itself, after the adjustment of the other variables. Conclusion: The HRQL improves after six months of the MRS, depression diminishes, whereas the SC did not show any alteration, confirming the stability of the construct. After the adjustment in the model of regression towards the variables: sex, age and depression in the pre-operatory period, SC explains 18,7% of postoperatory depression, an important result regarding it is a psychosocial variable. (AU)