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| Author(s): |
Viviane Grassi
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | Piracicaba. |
| Institution: | Universidade de São Paulo (USP). Centro de Energia Nuclear na Agricultura (CENA/STB) |
| Defense date: | 2008-06-23 |
| Examining board members: |
Elias Ayres Guidetti Zagatto;
Marcos Yassuo Kamogawa;
Jorge Cesar Masini;
Efraim Lázaro Reis;
Jarbas Jose Rodrigues Rohwedder
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| Advisor: | Elias Ayres Guidetti Zagatto |
| Abstract | |
Molecularly imprinted polymers (MIPs) are promising as material to be used in solid phase extractions due to their high selectivity. MIPs selectivity is directly related to the recognition of a molecule of interest, which was previously employed as template in the synthesis process. The main favorable characteristics of MIPs are the easy preparation, low cost, possibility of synthesis in adverse environments, and chemical resistance in the presence of acids, bases, metal ions, organic solvents as well as the physical resistance to high temperatures and pressures. In the present work, flow systems with molecularly imprinted polymers as in-line solid phase extractors were designed, and their characteristics and efficiencies were assessed in relation to the spectrophotometric determinations of the catechol, ascorbic acid and atrazine in environmental, pharmacological and food samples. Moreover, the feasibility of chiral separation was investigated in relation to D and L-ascorbic acid. Potentialities and limitations of implementing MIPs in flow analysis were highlighted (AU) | |