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Middle-ear and growth functions on the responses of the otoacoustic emissions

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Author(s):
Ualace de Paula Campos
Total Authors: 1
Document type: Doctoral Thesis
Press: São Paulo.
Institution: Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD)
Defense date:
Examining board members:
Renata Mota Mamede de Carvallo; Marisa Frasson de Azevedo; Alessandra Spada Durante; Carla Gentile Matas; Eliane Schochat
Advisor: Renata Mota Mamede de Carvallo
Abstract

INTRODUCTION: The Distortion Product Otoacoustic Emissions Input/Output function (DPOAE I/O function) is a subdivision of DPOAE, where the response amplitude is recorded such as a systematic growth function in the primary tones. The DPOAE I/O function provides specific parameters about the DPOAEs threshold and non-linearity. However, the response variability reduces the measure reliability to evaluate the cochlear robustness and the relationship between robustness and hearing thresholds. OBJECTIVE: This research studied the interaction between the tympanometric measures and cochlear functions measures in young adults without hearing complaints, considering the variables: middle-ear alteration antecedents, gender and right / left ear. METHODS: 69 normal hearing subjects, aged from 18 to 34 years participated of the study. From the total, 21 were men and 48 women. To reach the proposed objectives, the middle ear conditions were assessed by anamneses and 226 and 1000 Hz admittance probe-tone tympanometry. The audiometric thresholds were searched with 01 dBHL resolution to enable refined comparisons among pure-tone audiometry and DP-Gram amplitude and DPOAE I/O function thresholds. The gender and ear interference were also evaluated in all analyses. RESULTS/DISCUSSION: The results showed that the variables gender, antecedents and ear affected the I/O functions responses, but only the middle-ear alterations antecedents presented a constant modification pattern. In other words, the group with antecedents presented mainly reduced responses in comparison with no antecedents group. The audiometric thresholds also presented high correlation with DPOAE amplitudes and DPOAE I/O functions thresholds, after the detection of the variables affecting the results. As the background noise was controlled during this study, the results confirmed the importance of monitoring these variables in the normal hearing group compositions to perform researches with DPOAE. Regarding the DPOAE I/O functions (slope and threshold), the growth pattern was modified according the middle ear conditions, verified by the antecedents of middle ear alterations and 1000 Hz admittance probe-tone tympanometry. CONCLUSION: The DPOAE I/O function threshold studied presented positive correlation with audiometric thresholds and negative correlation with DP-Gram. The DPOAE I/O functions slope also showed high correlation with antecedents of middle ear alterations, denoting the potential value of this measure in the study of the healthy and damaged cochlear function and, hence, it possible application in amplification prescriptive measures (AU)

FAPESP's process: 08/05151-9 - Middle ear and growth rate effect in DPOAE responses
Grantee:Ualace de Paula Campos
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)