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Study of Gastric Dynamic and esophageal transit in scintigraphic images through Demons Tecnique

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Author(s):
Michele Noccioli de Souza
Total Authors: 1
Document type: Master's Dissertation
Press: Ribeirão Preto.
Institution: Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (PCARP/BC)
Defense date:
Examining board members:
Eder Rezende Moraes; Jose Ricardo de Arruda Miranda; Luiz Ernesto de Almeida Troncon
Advisor: Eder Rezende Moraes
Abstract

The goal of this project is to evaluate the gastric dinamic and the Oro-esophageal transit in scintigraphic images trough an optical flow tecnique called Improved Demons Tecnique. This tecnique provides the velocity of the pixels (also called, Deformation Force - DF) in sequencial images by pairs trough 3 image features: gradient, intensity of the pixels and orthogonal gradient information. To achieve our goal, scintigraphic images from Hospital das Clínicas of Ribeirão Preto database were used. This images were acquired trough 2 protocols: Oro-Esophageal Transit and Gastric Filling. At the Oro-Esophageal Transit protocol, images from 9 healthy volunteers were chosen. The volunteers, under a fasting of at least 8 hours, made ten swallows of 5 ml saline. The swallows number 1, 4, 7 and 10 were made with the saline labelled with about 26 MBq (about 700 µCi) 99mTc-phytate and acquired, by gamma-camera, as a set of 240 images per swallowing. The images acquired under the protocol Oro-Esophageal Transit were corrected and registered. The velocity fields obtained were correlated to a tecnique capable of obtain the relative transit times of the bolus in each region of the oesophagus. A high inverse correlation were obtained between the velocities and the times of transit in the oesophagus as a whole, as expected. The mean of the velocities obtained in the proximal oesophagus approached considerably of the velocity of primary peristaltic pump described in literature. At the Gastric filling protocol, images from 13 healthy volunteers were chosen. The volunteers, under a fasting of at least 8 hours, ingested a liquid meal labeled with about 72 MBq (about 2 mCi) 99mTc-phytate while a set of 330 images were acquired by gamma-camera. This images were also corrected and registered. The velocity fields were summed for each pair of images acquired and the frequency of the magnitude of this summed field, in the time of acquisition, were analyzed by Fast Fourier Transform, with a bidirectional Butterworth filter, in sliding windows of 4 minutes. A mean of the frequencies per volunteer were obtained and, after, a mean and standard deviation for the sample of volunteers. It was made a t student test that showed that the sample mean of the frequency of the proximal estomach is consistent with the known frequency of the contraction for this region (1 contraction per minute). We also studied the distal region. It was observed a predominance of slider windows with frequencies close to the frequency known for contractions of distal stomach (3 contractions per minute) in most of the volunteers. The stomach contractions were also analyzed visually through the divergent of the velocity fields and the perimeter of the stomach in the acquired images. (AU)

FAPESP's process: 11/05011-5 - Study of gastric and esophagus dynamics on cintilographic images by demons technique
Grantee:Michele Noccioli de Souza
Support Opportunities: Scholarships in Brazil - Master