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GENERATION AND REPRODUCTION OF DNA SEQUENCES AND ANALYSIS OF POLYMORPHISMS AND MUTATIONS BY USING ERROR-CORRECTING CODES
| Document type: | Patente |
| Inventor(s): | Marcio de Castro Silva Filho; Reginaldo Palazzo Jr.; Andrea Santos Leite de Rocha; Luzinete Cristina Bonani de Faria; Joao Henrique Kleinschmidt |
| Applicant: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Universidade de São Paulo (USP) ; Universidade Estadual de Campinas (UNICAMP) |
| Deposit date: | August 2010, 19 |
| INPI register: | |
| IPC: | C07H 21/04 G06F 19/00 G01N 33/50 G06F 19/12 G06F 19/22 G06F 17/10 |
Abstract
The present invention relates to a method that uses error-coding codes for validating polymorphisms and mutations/alterations in a DNA sequence which encodes a polypeptide sequence. The present invention also relates to a digital communication system for carrying out the method, employing a model for the biological coding system which resembles the most efficient digital communication. The method and digital communication system may be useful for the predictive analysis of diseases originated by mutations or polymorphisms in genes.
| FAPESP's process: | 02/07473-7 - Geometrically uniform codes in homogeneous spaces |
| Grantee: | Sueli Irene Rodrigues Costa |
| Principal Investigator: | Sueli Irene Rodrigues Costa |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Instituto de Matemática, Estatística e Computação Científica (IMECC) |
| Support Opportunities: | Research Projects - Thematic Grants |