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(EN) USE OF CYANOGLUCOSIDES AND PHARMACEUTICAL FORMULATIONS THEREOF IN THE TREATMENT OF DIABETES
| Office | WIPO |
| Document type: | Patent |
| Inventor(s): | Luiz Leonardo Saldanha; Anne Lígia Dokkedal Bosqueiro; José Roberto Bosqueiro; Nathalia Aparecida De Paula Camaforte Henriques; Priscilla Maria Ponce Vareda; Wagner Vilegas; Emerson Ferreira Queiroz; Laurence Marcourt; Jean Wolfender-Luc |
| Applicant: | Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp); Université de Genève |
| Year: | 2016 |
| Application Number: | PCT/BR2016/050148 |
| IPC: | A61K 31/275 A61K 31/7028 A61P 3/00 A61P 3/10 |
Abstract
The present Invention relates to the use of cyanoglucoside according to formula (I) and formulations thereof in the prevention and/or treatment of diabetes and/or metabolic syndrome; wherein R1, R2 and R3 are independently selected from an optionally substituted mono- or di- saccharide, -O-R4, -O- C(O)-R4 and halogen such as CI, F or Br, wherein R4 is selected from H, alkyl such as methyl, as well as tautomers, geometrical isomers, optically active forms, pharmaceutically acceptable salts and pharmaceutically active derivative thereof.
| FAPESP's process: | 09/52237-9 - Standardized herbal medicines for the treatment of chronic diseases |
| Grantee: | Wagner Vilegas |
| Principal Investigator: | Wagner Vilegas |
| Institution: | Universidade Estadual Paulista (UNESP). Campus Experimental do Litoral Paulista. Instituto de Biociências (IB-CLP) |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |