BIOACTIVE VITREOUS COMPOSITION AND ITS USE FOR BONE REGENERATION
| Document type: | Patente |
| Inventor(s): | João Henrique Lopes; Celso Aparecido Bertran; Lucas Pereira Lopes de Souza; Italo Odone Mazali; José Angelo Camilli |
| Applicant: | Universidade Estadual de Campinas (UNICAMP) |
| Deposit date: | December 2015, 15 |
| INPI register: | |
| IPC: | C03C 3/097 C03C 3/087 C03C 3/062 C03C 3/076 A61F 2/28 A61L 24/02 |
(EN) The present invention relates to a bioactive vitreous composition comprising niobium oxide, and to the use thereof for bone regeneration. The present invention pertains to the field of the chemistry of scaffold-comprising materials for bone tissue engineering and osteoregenerative medicine, and is aimed at correcting bone defects caused by diseases or accidents. The present application relates to a bioactive vitreous composition (bioglass) comprising from 40 to 55 mol% SiO2, from 23 to 33 mol% CaO, from 20 to 30 mol% Na2O, from 0.001 to 5 mol% P2O5 and from 0.001 to 5 mol% Nb2O5. This composition has medical and odontological uses as bone filling material, as scaffold for bone tissue engineering, for bioactive coatings and for the treatment of dentin hypersensitivity.
| FAPESP's process: | 10/05394-9 - Bioglasses derived from 45S5: effects of Nb2O5 or surface modification with Ca2+ on the glass structure and bioactivity |
| Grantee: | João Henrique Lopes |
| Principal Investigator: | Celso Aparecido Bertran |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) |
| Support Opportunities: | Scholarships in Brazil - Doctorate |