| Document type: | Patente |
| Inventor(s): | CLAUDIA PATRICIA MARIN ABADIA (UFSCar); MURILO CAMURI CROVACE (UFSCar); EDGAR DUTRA ZANOTTO (UFSCar); MARINA TREVELIN SOUZA (UFSCar) e CLEVER RICARDO CHINAGLIA (UFSCar). |
| Applicant: | Fundação Universidade Federal de São Carlos (UFSCar) ; Vetra Pesquisa e Desenvolvimento de Produtos Ceramicos de Alta Tecnologia LTDA. |
| Deposit date: | August 2021, 31 |
| INPI register: | |
| IPC: | A61F 2/02 C03C 4/00 A61L 27/10 C04B 35/14 A61L 27/56 A61F 2/28 C03C 3/00 A61L 27/02 B29C 67/04 C03C 12/00 C04B 35/16 C04B 35/634 C04B 38/06 |
(EN) The invention describes a method for preparing bone grafts from a preparation of a Biosilicate® in (110), in (120) infiltrating barbotine Biosilicate® into the Biosilicate® from (110), in (130) burning the infiltrated Biosilicate® from (120), in (140) infiltrating the burned Biosilicate® from (130) with Bioglass F18, in (150) burning the product from (140), in (160) repeating the infiltration with Bioglass F18 from (140) and the burning from (150), and in (170) recovering the Biosilicate®/Bioglass F18 product with improved compression strength. The bone grafts obtained have a porosity from 83.0 ± 2%, a mean cell size of 770 ± 290 μm, and a compression strength of 1.0 ± 0.2 MPa at 82,0 ± 1.3% porosity, a mean cell size of 525 ± 220 μm and a compression strength of 3.3 ± 0.3 MPa when prepared respectively from PU foams with 35 ppi or 45 ppi. The bone grafts obtained are used to replace trabecular bone and to provide consistent mechanical integrity and porosity for the regeneration of functional bone tissue.
| FAPESP's process: | 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass |
| Grantee: | Edgar Dutra Zanotto |
| Principal Investigator: | Edgar Dutra Zanotto |
| Institution: | Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Exatas e de Tecnologia (CCET) |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |