CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Vanderlan da Silva Bolzani is full professor at Sao Paulo State University (UNESP). Fellow of the Royal Society of Chemistry (UK), member of the Brazilian Academy of Science (ABC) and São Paulo Academy of Science (ACIESP), is also Science Productivity CNPq Fellow level 1A, and has received several awards; the most recently is Distinguished Woman in Science Chemistry and Chemical Engineering, conceived by ACS IUPAC and Simão Mathias Medal and Elsevier-Capes in 2013. With Ph.D. in Organic Chemistry, under guidance of Professor Otto Richard Gottlieb, at University of São Paulo, in 1990 she was awarded with a fellowship from DAAD for a short training at University of Hannover. After a post-doctorate at Virginia Polytechnic Institute (VPISU-USA) under guidance of Professor David Kingston, she joined to the São Paulo State University (UNESP), and since 2003, is member of the Biota-FAPESP Program Coordination. Currently is Director of the UNESP Technology Transfer Office (UNESP-AUIN). Her field of interest is plant science, and has been involved in the isolation, bioactivity and function of secondary metabolites and peptides from plants. Also she has studied biosynthesis of piperidine alkaloids, and recently has been involved on metabolomics of medicinal plants. She has had strong involvement in human resource training, with 0ver 50 Master and PhD students and several Post-doctoral supervisions. She has been invited to give lectures and seminars Worldwide. Has published more than 344 articles (Index h=26, 2522 citations) 5 book chapters and 7 patents. Also has strong work collaboration with National Pharmaceutical and Cosmetic Industries looking for new drugs from plants species. Dr. Bolzani was President of the Brazilian Chemical Society from 2008-2010, and is currently Counselor. She serves as member of Editorial Boards of several Scientific Journals as Journal Natural Products, Natural Products Reports, Phytochemistry Letters and Journal of Ethnopharmacology. Since 2011 is a visiting professor at the Enzymologie Moléculaire et Fonctionnelle UR4-UPMC, Paris, and in 2012 became member of the LOreal Scientific Advisory Board. In October 2013 was elected for the World Academy of Science for the Advancement of Science in Developing Countries, (TWAS). (Source: Lattes Curriculum)
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Brazil is a country with one of the greatest bio-diversities in the world, accounting for ca. 10% of all living species. It comprises six terrestrial biomes, the Amazonian rainforest, Caatinga, Cerrado (Savanna), Atlantic forest, Pantanal and Pampas. This extraordinary biodiversity and its chemical diversity could be used for the development of bioproducts, including pharmaceuticals, cosm…
The Center for Research and Innovation in Biodiversity and Drug Discovery (CIBFar) is a joint initiative resulting from existing collaborative research projects, including the Physics Institute of São Carlos (IFSC) and the School of Pharmaceutical Sciences of Ribeirão Preto at the University of São Paulo (USP), the Institute of Chemistry at the State University of São Paulo (UNESP), the I…
This project involves the update of NuBBE Database semantic web for interoperability and metadata analysis of natural products. The biodiversity of tropical environments offers a particularly valuable potential in chemical diversity of natural products, the most traditional source for the development of new drugs. The NuBBE Database (NuBBEDB) is the first natural product library from Braz…
(Only some records are available in English at this moment)
(Only some records are available in English at this moment)
Considering the magnitude of Brazilian biodiversity, there are still few studies on natural products biosynthesized by plant species that occur in six different biomes, a valuable collection of scientific and applied research that is still little studied and economically explored. The Bignoniaceae family, composed of approximately 800 species, is widely distributed throughout the national…
Cyclopeptides from plants can be understood as cyclic compounds formed mainly by peptide bonds containing 2-37 amino acids, where most of the amino acids are from the L-amino acid series. Based on their chemical skeletons and ecological distribution, peptides from plants can be classified into two major classes (homocyclopeptides and heterocyclopeptides), five subclasses (heteromonocyclop…
One of the research areas of the NuBBE group (Nucleus of Biosynthesis, Bioassays, and Ecophysiology of Natural Products) at the Araraquara Chemistry Institute (UNESP) focuses on the identification of novel cyclic peptides produced by plants, a field of natural product research that is still understudied in Brazil and was started at NuBBE. The studies of peptides in the Annonaceae taxon, …
Arboviruses like dengue, zika and chikungunya have become a global health crisis. In Brazil, transmission of arboviruses by Aedes aegypit vector has profound impacts at the health system, where vaccines and drugs for these diseases are non-existent. The control of vector spreading by insecticides has been the most used way, but resistance by mosquitoes and toxicity to humans become those …
(Only some records are available in English at this moment)
Peptides play an important role in several cellular processes in living organisms, including plants. Cyclic peptides (orbitides) consist in a new class of compounds recently investigated for natural products, and still little explored in Brazil. It is also known that the presence of these substances are restricted to certains groups of taxa. Thus, the investigation of this class of compou…
The extracts of medicinal plants present a great metabolic diversity, and thus have a large amount of bioactive compounds which may have potential as therapeutic agents. They also can be a starting point for the development of new prototypes and play a significant role in drug discovery. The Nucleus for Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE) at the Institute…
Chiral molecules are characterized by three-dimensional handedness and can exist in two enantiomeric forms of opposite absolute configuration (AC). Most natural products and biologically active compounds are chiral and their biological and molecular functions are closely related to their chirality, that is, AC and conformation. Therefore, the unambiguous determination of the AC and confor…
| 5 / 5 | Ongoing research grants |
| 34 / 19 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 61 / 38 | Completed scholarships in Brazil |
| 4 / 3 | Completed scholarships abroad |
| 107 / 68 | All research grants and scholarships |
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