CV Lattes
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Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Undergraduate at Veterinary Medicine and Residency in Small Animal Clinic and Surgery at the Faculty of Veterinary Medicine and Animal Science of University of São Paulo (USP). PhD in Human Physiology by the Institute of Biomedical Sciences of USP and Post-Doctorate in Renal Physiology from the University of California at San Francisco (USA). PhD Professor at the Department of Veterinary Medicine of Faculty of Animal Science and Food Engineering (FZEA/USP) Research activities: Renal Physiology (involving the effects of aldosterone on ion transport and the mechanism of renal injury), Cardiac electrophysiology and Medical Clinic of dogs and cats. (Source: Lattes Curriculum)
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The normal glomerular function depends on the integrity, differentiation and adhesion of the podocytes to the glomerular basement membrane, both components of the glomerular filtration barrier (GFB). The detachment and loss of podocytes through the urine (podocyturia) occurs naturally, but may increase in disease, being accompanied by proteinuria. In chronic kidney disease (CKD), irrevers…
Recently, many researchers believed that aldosterone modulated only the distal nephron ion transport by genomic pathway. However, our recent publications demonstrate genomic and nongenomic effects of aldosterone in proximal tubule (S2 and S3 segments) and the participation of mineralocorticoid receptor (MR) in genomic effects. The receptor and the nongenomic signaling pathways are still u…
The obese dogs present systemics and laboratory abnormalities compatible with inflammation. The expansion of white adipose tissue appears to be the key to the inflammatory process, in part by the infiltration of a large number of macrophages. The microRNAs (miRNAs) present in adipose tissue and circulating extracellular vesicles (VEs), appears to control this process in humans; however, s…
Due to veterinary medicine advances, dogs are living longer and elderly patients with cognitive dysfunction are part of the clinical routine. In addition, hypercortisolism may be related to cognitive dysfunction, because the cortisol excess changes the structure and functions of the hippocampus: the brain area responsible for learning and memory. Therefore, it is relevant to study the rel…
Aldosterone is a steroid hormone that plays an important role in body fluid and electrolyte homeostasis. Studies in models of hypertension, induced by aldosterone and sodium treatment, showed renal and cardiovascular inflammation. However, such experiments did not show the influence that chronic and exclusive treatment with aldosterone (no supplementation with NaCl) has on kidney inflamma…
(Only some records are available in English at this moment)
| 3 / 2 | Completed research grants |
| 12 / 11 | Completed scholarships in Brazil |
| 15 / 13 | All research grants and scholarships |
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