CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Pharmacist at ((FCF-UNESP Araraquara-SP ) (2011), and MSc and PHD in Pharmaceutical Sciences at the same university. Research Internship at Medicinal Chemistry Laboratory of the University of Turin, Italy (Scholarship -FAPESP 2013 / 04244-1 ) . Expertise in Drug Discovery and Development (Source: Lattes Curriculum)
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The Sickle Cell Anemia (SCD) is a genetic blood disease characterized by a mutation in the ² -hemoglobin gene. This mutation promotes polymerization of hemoglobin molecules, in situations of low oxygen tension, which alter the structure of the erythrocyte cytoskeleton promoting changes in its physical structure (sickling). Furthermore, there is an increased adhesion of cells to the blood …
Sickle cell disease (SCD) is an hereditary chronic hemolytic anemia characterized by the presence of red blood cells that when deprived of oxygen, take the form of sickle. It has been reported that patients with SCD have increased circulating levels of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha). Hydroxyurea (HU) is the most widely drug used for treatment and…
Sickle Cell Disease (SCD) is one of the most prevalent inherited blood disorders. This genetic disease is characterized by a single substitution of aminoacids (glutamic acid to valine) at the ²-globin chain leading to hemoglobin polymerization at low oxygen environment. The sickle-shaped cells have exhibited high adherence to the vascular endothelium and contribute to inflammatory panel…
Sickle cell anemia (SCA) is a hereditary hemoglobinopathy characterized by a pumctual mutation at sixth codon of beta-globin gene, resulting in the replacement of a glutamic acid for valine at beta-globin chain. This modification promotes, at low oxygen concentrations, polymerization of hemoglobin molecules that alters the structure of the erythrocyte cytoskeleton (sickling) or cause eryt…
| 2 / 2 | Completed scholarships in Brazil |
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