Paula Comune Pennacchi
CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Post-doctoral at Spanish National Research Cancer Centre - CNIO, in Madrid, Spain. Post-doc at School of Pharmacy - USP, Department of Clinical Chemistry and Toxicology (CAPES 7) PDJ-CNPq INCT (150158/2016-5). PhD by School of Pharmacy - USP, Department of Clinical Chemistry and Toxicology (CAPES 7), FAPESP (2012 - 2016). MSc degree in Human Physiology by Sociedade Brasileira de Fisiologia (SBFis), FAPEMIG (2009 - 2011). Bachelor in Biology by Universidade Federal de Alfenas Unifal-MG (2005 - 2008). Collaborated with RENAMA-CNPq-MCTI in the development of reconstructed human skins as alternative method to replacement of animal experimentation (2012 - 2015). Interested in research innovation, development of alternative methods to replacement of animal use in research. Experienced in the development of "in vitro" models: organotypic cultures and ?in vitro? reconstruction of human organs and tissues. Development of full thickness reconstructed human skin and epidermal equivalents for cytotoxicity assays for safety and efficacy of plant extracts, pharmacological/cosmetics compounds, melanoma invasion and aging of skin. (Source: Lattes Curriculum)
- Development of artificial skin containing glycated dermal equivalent mimicking the pathophysiology of skin aging and diabetes, BP.DR
Abstract
The nonenzymatic glycation of proteins (AGEs) is a common factor to the pathophysiology of a number of disorders related to aging and diseases such as diabetes mellitus (DM). The generation of AGEs products is through the reactions of non-enzymatic glycation of extracellular matrix in the dermis and have been touted as one of the factors responsible for disability and loss of elasticity...
| 1 / 1 | Completed scholarships in Brazil |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 4 |
| Citations | 27 |
| Cit./Article | 6.8 |
| Data from Web of Science | |
IMMICH, A. P. S.; PENNACCHI, P. C.; NAVES, A. F.; FELISBINO, S. L.; BOEMO, R. L.; MARIA-ENGLER, S. S.; CATALANI, L. H.. Improved tympanic membrane regeneration after myringoplastic surgery using an artificial biograft. Materials Science & Engineering C-Materials for Biological Applications, v. 73, p. 48-58, APR 1 2017. Web of Science Citations: 4. (11/18017-1, 11/22812-1, 11/21442-6)
CATARINO, CAROLINA MOTTER; PEDROSA, TATIANA DO NASCIMENTO; PENNACCHI, PAULA COMUNE; DE ASSIS, SILVIA ROMANO; GIMENES, FABRICIA; LOPES CONSOLARO, MARCIA EDILAINE; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. Skin corrosion test: a comparison between reconstructed human epidermis and full thickness skin models. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, v. 125, p. 51-57, APR 2018. Web of Science Citations: 1. (11/07441-7, 11/22812-1, 11/14327-6, 13/00735-0, 13/12682-9)
PENNACCHI, PAULA COMUNE; SOARES DE ALMEIDA, MAIRA ESTANISLAU; ALVES GOMES, OCTAVIO LUIS; FAIAO-FLORES, FERNANDA; DE ARAUJO CREPALDI, MARIA CLARA; DOS SANTOS, MARINILCE FAGUNDES; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. Glycated Reconstructed Human Skin as a Platform to Study the Pathogenesis of Skin Aging. TISSUE ENGINEERING PART A, v. 21, n. 17-18, p. 2417-2425, SEP 1 2015. Web of Science Citations: 16. (11/07441-7, 11/22812-1, 11/14327-6)
PEDROSA, TATIANA DO NASCIMENTO; CATARINO, CAROLINA MOTTER; PENNACCHI, PAULA COMUNE; DE ASSIS, SILVIA ROMANO; GIMENES, FABRICIA; LOPES CONSOLARO, MARCIA EDILAINE; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. A new reconstructed human epidermis for in vitro skin irritation testing. TOXICOLOGY IN VITRO, v. 42, p. 31-37, AUG 2017. Web of Science Citations: 6. (11/07441-7, 11/14327-6, 13/12682-9, 14/24400-0, 11/22812-1, 13/00735-0)