CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Ciencias Biologicas from Universidade Estadual de Campinas (1995), master's at Bioquímica from Universidade Estadual de Campinas (1999) and Ph.D. at Clinical Medicine from Universidade Estadual de Campinas (2004). Has experience in Biochemistry, focusing on metabolic disturbances and programming, acting on the following subjects: cell signaling, obesity, diabetes and epigenetics. (Source: Lattes Curriculum)
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Numerous diseases, in which the inflammatory process plays an important role in pathophysiology, have a high prevalence in the population, such as obesity, diabetes, cardiovascular diseases, cancer, and inflammatory bowel diseases. The immune system utilizes inflammatory processes to act against infectious agents, but excessive activation can have consequences for the organism. The alpha7…
Studies in the field of Developmental Origins of Health and Disease (DOHaD) have shown that the self-perpetuation of obesity is related to metabolic programming resulting from critical periods of development. Obesity is closely related to subclinical inflammation, and recent work from our group has demonstrated that exposure to an obesogenic diet promotes impairments in the anti-inflammat…
In both human and animal organisms, tissues can be individually programmed in critical periods of development, such as intrauterine life, in order to modulate their response to different environments after birth. Such modulation, in the long term, can lead to the development of diseases such as obesity and metabolic syndrome. In the US and Brazil, obesity and the metabolic syndrome are on…
In recent decades, obesity and the metabolic syndrome have become increasingly prevalent in the world population. Recently the consequences of lipid overload during critical periods of development on the metabolism of offspring, through epigenetic changes, have been evidenced contributing to the development of obesity and its complications, such as hepatic steatosis. Among the epigenetic …
(Only some records are available in English at this moment)
Studies in the field of Developmental Origins of Health and Disease (DOHaD) have shown that the self-perpetuation of obesity is related to metabolic programming resulting from critical periods of development. Obesity is closely related to subclinical inflammation, and recent work from our group has demonstrated that exposure to an obesogenic diet promotes impairments in the anti-inflammat…
MicroRNAs (miRNAs) are small molecules of non-coding RNAs whose primary function is the modulation of gene expression through the interaction with target messenger RNA (s). MiRNAs can be released into extracellular fluids and transported in different ways, namely I) internalized in extracellular vesicles, such as exosomes and microvesicles; II) vesicles free miRNA, bound to the Ago2 prote…
In the last decades, the supply and consumption of ultra-processed foods rich in calories andsaturated fat has become more frequent, contributing to the extensive expansion of obesityconditions around the globe. Obesity is a multifactorial disease characterized by excessadiposity that compromises the individual's health. It is currently known that a maternalobesogenic environment can caus…
The number of obese in the world population is directly associated with the increase in the prevalence of Non Alcoholic Fatty Liver Disease (NAFLD), condition in which there is accumulation of triglycerides (TAG) in the liver, which can lead to non-alcoholic steatohepatitis (NASH), with progression to fibrosis, cirrhosis and hepatocarcinoma. It is known that hepatic lipid metabolism can b…
In recent decades, obesity and metabolic syndrome have become diseases of high prevalence worldwide. Changes in lifestyle and eating habits, especially during critical periods of development, lead the progeny to important metabolic alterations through epigenetic mechanisms, such as modulation of miRNA expression, contributing to the maintenance of a "vicious cycle" of obesity and its como…
(Only some records are available in English at this moment)
The obesity has acquired epidemic characteristics and the same numbers that indicate the increase in obesity also showed a significant increase in individuals with diabetes mellitus type II. It is now known that both diseases exhibit a metabolic response characteristic, which leads to changes in intracellular signaling pathways and glucose homeostasis. High fat diet (HFD) consumption is r…
| 2 / 2 | Ongoing grants |
| 9 / 8 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 11 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 25 / 20 | All research grants and scholarships |
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