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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Rafael Ricci de Azevedo in research grants and scholarships supported by FAPESP.
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Toxoplasma gondii is an obligate intracellular parasite that causes toxoplasmosis. To infect host cells, T. gondii tachyzoites, besides other events, release proteins contained in organelles called micronemes located in the apical region of the parasite. Concerning the microneme proteins (TgMICs), our group isolated the TgMIC1/TgMIC4 subcomplex, whose constituents are lectins that induce …
Interest in studying neutrophils has been increased in recent years among many research groups, which look for characterizing new functions and identifying the role exerted by neutrophils in different pathologies. Numerous obligatory or facultative intracellular pathogens can escape from neutrophil responses and thus live and reproduce in the host organism. Some pathogens modulate neutrop…
The study of ArtinM, a lectin obtained from seeds of Artocarpus heterophyllus, is interest due its important immunomodulatory activity, which induces protection against several intracellular pathogens such as Leishmania major, Listeria monocytogenes and Paracoccidioides brasiliensis. This protection is triggered by the recognition of glycans by ArtinM on receptors of immune cells surface …
Interest in studying neutrophil biology is growing more and more due to the importance of these cells in inflammatory and infectious diseases. Neutrophils are the first cells to respond to microbes and some pathogens can modulate the function of these cells to succeed in the infection process. Because of that it is mandatory to understand in deep the relationship of neutrophils with those…
By interacting with glycoconjugates on the surface of immune cells, lectins can trigger cell activation and work as valuable immunomodulatory agents. Our research group has been working with plant and microbial lectins that induce efficient responses against infection by intracellular pathogens. Some of these lectins act on neutrophils, triggering migration, degranulation, cytokine releas…
| 5 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 7 / 5 | All Scholarships |
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