CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Maria Jose S. Mendes Giannini is a Ph.D. at Microbiology from Universidade de São Paulo. She developed activity in the mycology laboratory of the Medical School of USP from 1977-82. Since 1983 she is a professor of UNESP and currently Researcher of CNPq 1B. She was a Supervisor of the Community Assistance Center, Faculty of Pharmaceutical Sciences of Araraquara - UNESP, in 1991-92. She was vice- director of the Faculty of Pharmaceutical Sciences UNESP and coordinator of the Graduate Program in Bioscience and Biotechnology Applied to Pharmacy (Clinical Analysis). Editor of the Journal of Pharmaceutical Sciences - UNESP. Co-editor of the Journal of Basic and Applied Pharmaceutical Sciences, from 2005. Member of the editorial board of the Journal: Brazilian Journal of Pharmaceutical Sciences and the Journal of the Institute Adolfo Lutz. Member of the Committee responsible for the Plan of Institutional Development of UNESP. She was adviser to the Board of Education and Research (CEPE) and Graduate Studies (PROPG) at UNESP. Vice-President of the Brazilian Society of Mycology (2000-02) and Microbiology (2006-09). It is part of the consultant of CAPES, FAPESP, FINEP and CNPq and attended the last two triennial evaluations - CAPES program Graduate of the area of Pharmacy. She has experience in Pharmacy with emphasis in Mycology and Cellular Biology, acting on the following topics: fungus-host interaction, molecular epidemiology and bioprospecting of substances and antibodies with antifungal activity. It is group leader of CNPq: fungus-host interaction. Develop projects on the National Institute of Science and Technology for Pharmaceutical Innovation INCT_if. Maintains technical-scientific collaboration with researchers working in the area of cell biology and Mycology from international institutions (National University of Mexico, UNAM; Institute Carlos III, Madrid, Spain; the University of Texas; Institute of Molecular Medicine, Lisbon, Portugal) and from national (UFG, UFRGS, USP, UFPe, UFRGN) and UNESP. She is currently Research vice-rector of UNESP and member of the Board of FAPESP. (Source: Lattes Curriculum)
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Dermatophytes are fungi that affect keratinized tissues such as skin, hair, and nails, causing dermatophytoses. The main agents can be anthropophilic (Trichophyton rubrum and the Trichophyton mentagrophytes/T. interdigitale complex) and zoophilic (Microsporum canis). In some cases, the lesions of these fungi are associated with bacteria and yeasts, resulting in an aggravated infectious co…
Fungal infections are neglected by the social and political point of view. However, these affect more than one billion people, resulting in approximately 11.5 million deadly infections and more than 1 to 5 million deaths per year. Despite advances in several public health areas, many pathogens remain important because of their pathogenicity and represent an important source of infection f…
The biofilm formation by microorganisms and their potential health damage have been gaining prominence in recent years since it is resistant to antimicrobial communities, to the immune response and the adverse environmental conditions. The description of filamentous fungi, in particular the dermatophytes as capable of surviving in communities is recent, worrying and may be related to the …
(Only some records are available in English at this moment)
Candida auris was first identified in 2009 in Japan and has since been found on every continent, becoming a serious public health concern due to outbreaks in healthcare facilities and its rapid ability to develop resistance to available antifungal drugs. Unlike other Candida species, which preferentially colonize mucous membranes and the gastrointestinal tract, C. auris shows tropism for …
Dermatophytoses are fungal infections caused by filamentous fungi that affect keratinized structures such as skin, hair, and nails. Microsporum canis, a zoophilic species, is of particular importance due to its ability to infect humans and companion animals, such as dogs and cats. The ability of these fungi to form biofilms has been associated with resistance to antifungal treatments and …
Paracoccidioidomycosis is a systemic mycosis caused by the thermodimorphic pathogenic fungus ofthe genus Paracoccidioides. It is considered a neglected tropical disease of great importance in Latin American countries, mainly affecting rural workers. Several factors determining virulence, such as dimorphism, changes in cell wall composition, adhesins, and biofilm formation, have been repor…
Dermatophytes are filamentous keratinophilic fungi, agents of dermatophytosis, also more commonly known as "tinha" or "tinea," mycoses with a high global incidence capable of developing exclusively on tissues with keratin, such as nails, hair, and skin. The main agents can be anthropophilic and zoophilic. Several virulence factors are involved in the pathogenicity of dermatophytosis. The …
Dermatophytes are fungi that infect keratinized tissues such as skin, hair, and nails, causing dermatophytosis. There is an association between these fungi' lesions with bacteria, in some cases, making treatment more difficult in some cases. Such infections have a high global incidence and are of great interest to public health. Although some of these fungi can form monospecies biofilms, …
Dermatomycoses are mainly caused by fungi of the dermatophyte family and yeast species of the genera Candida. Dermatophytosis is a superficial infection of keratinized structures such as skin, hair and nails caused by filamentous fungi of the family Arthrodermataceae. The main genera are Microsporum, Epidermophyton, Trichophyton. Among the yeast, some species of the genus Candida are norm…
(Only some records are available in English at this moment)
Cryptococcus spp. cause invasive fungal infections, which are responsible for high rates of morbidity and mortality. The fungus can transfer among macrophages by both lytic and non-lytic methods, facilitating dissemination within the host organism. Previous studies have identified a key role for cryptococcal extracellular vesicles (EVs) in regulating the proliferation of this fungus withi…
Phosphorylation state of any protein is the result of a balance between the activities of kinases and phosphatases (PPases), that can modify the protein functions. Recently due to a better understanding of the regulatory mechanisms of the cell cycle, there is a growing appreciation for the role of PPases in this process, since the coordination of cell growth with division is essential for…
Paracoccidioides brasiliensis and P. lutzii are dimorphic fungi, etiologic agents of paracoccidioidomycosis (PCM). Fungi of Paracoccidioides genus have mechanisms that enable them to adhere and invade host tissues and adhesion is one of the most important steps in the Paracoccidioides infection, being responsible for differences in virulence of isolates of these fungi. Because of the impo…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 32 / 13 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 26 / 12 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 66 / 33 | All research grants and scholarships |
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