CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Fisioterapia from Universidade Federal de São Carlos (2001), ph.d. at Doutorado sanduíche from Loyola University of Chicago (2005) and ph.d. at Histology from Universidade de São Paulo (2005). Has experience in Morfologia, focusing on Morfologia, acting on the following subjects: lesão muscular esquelética sistêmica, crotoxina, orientações fisioterapêuticas, questionário de qualidade de vida para asmáticos and plasticidade muscular esquelética. (Source: Lattes Curriculum)
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Skeletal muscle has an appreciable regenerative capacity, which is especially attributed to the action of muscle stem cells called satellite cells. Additionally, fibro-adipogenic progenitor cells (FAPs) resident in the skeletal muscle provide a favorable niche for satellite cells to act during muscle regeneration. However, during aging, FAPs act inefficiently after muscle injury, accumula…
Satellite cells, a post-natal population of muscle stem cells, are important for post-natal muscle development because they fuse in order to promote the myofiber growth. In addition, satellite cells contribute to the maintenance of muscle mass integrity and are essential for the success of the remarkable regenerative process of skeletal muscle. Overall, skeletal muscle regeneration involv…
Marfan syndrome (SMF) is characterized by an autosomal dominant systemic disorder that affects connective tissue, since mutation occurs in the fibrillin-1 gene, with consequent alteration in the fibrillin-1 protein. Such protein is the main component of microfibrils present in the extracellular matrix of elastic and non-elastic connective tissues. Considering that: 1) the molecular mechan…
(Only some records are available in English at this moment)
Skeletal muscle is the most abundant organ in the body and has vast regenerative potential, attributed mainly to the protagonist muscle stem cells, called satellite cells. Fundamental in muscle growth, repair and regeneration, these cells are activated following muscle injury and are capable of recovering damaged myofibers. Furthermore, other cells, such as fibroadipogenic progenitor cell…
Skeletal muscle has a great ability to regenerate after injuries due to the action of muscle stem cells called satellite cells. Furthermore, after muscle damage, fibro-adipogenic progenitor cells (FAPs) resident in skeletal muscle are activated, proliferate and provide a favorable environment for the occurrence of muscle regeneration mediated by satellite cells. However, during aging, FAP…
It is known that the elastic deformation imposed on bones by muscle contraction stimulates bone formation, while inhibiting resorption, which favors the gain of bone mass. Considering that bone and skeletal muscle tissues secrete factors (osteokines and myokines, respectively) that act in other tissues or organs via paracrine and endocrine mechanisms, a new paradigm has been established t…
Skeletal muscle has a remarkable ability to regenerate after injury, which is attributed to the presence of muscle stem cells called satellite cells. In addition, after muscle injury, fibro- adipogenic progenitors (FAPs), mesenchymal interstitial cells residing in the skeletal muscle, are activated, proliferate and expand, and provide a transient favorable environment to promote satellite…
Skeletal muscle tissue has the ability to regenerate after injury. Satellite cells are stem cells specific of the skeletal muscle and play a fundamental role in the regeneration of this organ. Although the morphological aspects of skeletal muscle regeneration are well known, the molecular mechanisms of this process are still not completely understood. Considering that the Set1/Trithorax-t…
Marfan syndrome (SMF) is an autosomal dominant systemic disease that affects connective tissue due to mutations in the fibrillin-1 gene that cause alteration in fibrillin-1 protein, one of the major microfibril components of the extracellular matrix of connective tissue. Individuals with SMF have lower muscle mass characterized by reduced size and number of muscle fibers and consequent lo…
(Only some records are available in English at this moment)
Skeletal muscle has a great capacity to regenerate after injuries, due to the activity of muscle stem cells called satellite cells. Furthermore, after muscle damage, fibroadipogenic progenitor cells (FAPs) resident in skeletal muscle are activated, proliferate and provide a favorable environment for the occurrence of muscle regeneration mediated by satellite cells. On the other hand, elde…
Marfan syndrome is caused by mutations in an autosomal dominant gene encoding fibrillin-1, which is the key structural glycoprotein for microfibrils and act as scaffolding proteins for formation of elastic fibers and elastin deposition. Skeletal muscle alterations are also found in Marfan syndrome, such as reduction in the number and size of myofibers, combined with fibrosis, deposition o…
Skeletal muscle tissue has a remarkable capacity of repairing itself after injury. This regenerative capacity depends on satellite cells, the muscle stem cells that are crucial players in the regeneration process of the damaged myofibers. During aging this process is impaired, which is associated with the reduction in the number and the function of satellite cells in aged mice. The satell…
| 1 / 1 | Ongoing grants |
| 12 / 10 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 19 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 2 | Completed scholarships abroad |
| 39 / 28 | All research grants and scholarships |
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