graduation at Medicina Veterinária from Universidade de São Paulo (2003) and doctorate at Veterinary Medicine from Universidade de São Paulo (2008). Has experience in Veterinary Medicine, acting on the following subjects: guaraná, quimioprevenção, paullinia cupana, hepatocarcinogenese and pcna. (Source: Lattes Curriculum)
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The increase over the years in the number of people with cancer and cancer deaths, as well as the existence of cancers in different organs with heritable causes or not, are very similar to what happens in other animal species, especially those sharing the human environment as dogs and cats. In Brazil there are 55,1 and 24,7 million living dogs and cats respectively. Considering that 1 in …
The increase over the years in the number of people with cancer and cancer deaths, as well as the existence of cancers in different organs with heritable causes or not, are very similar to what happens in other animal species, especially those sharing the human environment as dogs and cats. In Brazil there are 55,1 and 24,7 million living dogs and cats respectively. Considering that 1 in …
The aim of this proposal is to bring an outstanding Visiting Researcher (Dr. David J. Argyle) in the area of Translational Veterinary Oncology to open new possibilities for the ongoing research projects at the Laboratory of Comparative and Translational Oncology (LOCT-USP) of the School of Animal Science and Food Engineering, University of Sao Paulo, Campus Fernando Costa at Pirassununga-…
This equipment has the main function the analysis of specific cell populations in a heterogenous sample, based on their specific properties such as markers or enzyme activity. It will be a multi-user equipment since it can be used for several different applications when one wants to characterize cell biology. (AU)
(Only some records are available in English at this moment)
Around 90% of oral melanomas in dogs are malignant and have a high rate of invasiveness with a propensity to metastatic to the lungs and regional lymph nodes. The life expectancy of animals affected by the disease is reduced, even after surgical treatment, reaching a maximum survival of 18 months. In this scenario, immunotherapy has shown promise and its success is precisely because it ca…
The human genome encodes more than 500 protein kinases, of which the majority remain to be explored for their structure and function. Also, there are at least 91 protein kinases that represent likely cancer drivers 1 and dysregulation of kinase function is a hallmark of most human cancers. As a result, kinase inhibitor development has been one of the major focuses of drug development duri…
Lymphoma is one of the most frequent type of cancer in cats and the pursuit of alternatives therapies is necessary, given the considerable number of animals that presents tumor recurrence or does not respond to the conventional treatment, which is mostly chemotherapy, a kind of therapy that has many coleteral effects. Besides, the presentation of coleteral effects is commum in comparison …
Considering the economic and sustainable impact of cattle selection for feed efficiency (FE), several proposals have emerged for the identification of efficient animals. Among them, the residual food intake (RFI) presents a great importance, butlow feasibility, due to the time and cost required for its measurement. One strategy to deal with this limitation would be the identification of a…
3D cells cultures have the advantage of mimicking the tumor microenviroment, and this makes these models ideal for evaluation of new cancer therapies, obtaining results that can be considered more reliable compared to 2D cultures in cell monolayers. Newcastle Disease Virus (NDV) is an oncolytic virus, non-pathogenic for mammals, which selectively induces oncolytic effects in cancer cells,…
Bovine production systems have an important environmental impact due to the production of methane from ruminal microbial fermentation. The generation of enteric methane is known to be associated with animal genetics and the rumen microbiome, it is also negatively associated with feed efficiency in cattle. The importance of viruses in the rumen ecosystem is still poorly understood, althoug…
(Only some records are available in English at this moment)
Metabolomics is a promising alternative aiming to define markers for residual feed intake (RFI) for selection of feed efficiency in beef cattle in a more accurate, faster, and cost-effective way. Studies evaluating metabolites associated with feed efficiency in beef cattle are still scarce and, for the most part, carried out on a small scale, generating discoveries that lack statistical r…
Exists at least 356 dog breeds recognized by the Federation Cynologique Internationale (FCI). The diversity of phenotypes associated with canine breeds reflects a large genomic variation, which has been shown to be much greater than in humans. Genomic variation also affects the immune repertoire, causing differences in the adaptive immune response, influencing the repertoire of B cell rec…
Selecting domestic animals for productive traits aims to meet human needs over time. Currently, the main goals for selecting beef cattle are to increase productivity, reduce environmental impact and the competition with humans for grains. One way to achieve these aims is to select efficient cattle, which is an important feature from a productive and economic point of view, as it enables t…
Mammary tumors are the most frequent type of cancer in female dogs as in women. Besides that, its cells share similar features and can be used to comparative studies and screening of antineoplastic agents. Epigenetic targets are highlighted as potential and innovative therapy against cancer. Both histone deacetylases (HDACs) and bromodomain and extraterminal proteins (BET) inhibitors have…
Canine lymphomas are a diverse group of cancers and are among the most common cancers diagnosed in dogs. There are over 30 described types of canine lymphoma, and these cancers vary tremendously in their behavior. Lymphomas may affect any organ in the body, but most commonly originate in lymph nodes, before spreading to other organs,such as the spleen, liver and bone marrow. Multicentric …
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 9 / 5 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 25 / 19 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 6 / 6 | Completed scholarships abroad |
| 47 / 37 | All research grants and scholarships |
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CV Lattes
ORCID