CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Cláudio Francisco Tormena is Full Professor of the Institute of Chemistry at University of Campinas Campinas - São Paulo - Brazil. He received his PhD (in chemistry) from University of Campinas in 2000, under supervision of Professor Roberto Rittner. Part of his doctoral was developed at the University of Liverpool from 1998 to 1999 under supervision of Professor R. J. Abraham. He was a postdoctoral fellow at the University of Campinas from 2000 to 2003. From 2009 to 2010 during a sabbatical period, Dr. Tormena stayed in the School of Chemistry at the University of Manchester working with Prof. Gareth A. Morris. He has published more than 166 peer-review papers and more than 100 communications in national and international meetings. His research interests are focused on the experimental and theoretical NMR parameters, conformational analysis and Matrix-Assisted DOSY for mixtures analyses and pulse sequence development. He is a member of Advisory board of Magnetic Resonance in Chemistry and member of São Paulo Academy of Science (Source: Lattes Curriculum)
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The application of Technical Reserve for Institutional Research, granted by FAPESP, concerning the year of 2024, was approved by the Congregation of the Institute of Chemistry on March 27. This grant will allow the complementing of the cabling construction of the research laboratories, a facility for the biofreezer and cell culture rooms. Finally, maintenance of institutional multi-user e…
The application of Technical Reserve for Institutional Research, granted by FAPESP, concerning the year of 2023, was approved by the Congregation of the Institute of Chemistry on August 28. This grant will allow the modernization of the cabling construction and payment of Storage and Switch Core contracts, maintenance of generator sets. Furthermore, it will allow the acquisition of a mach…
NMR spectroscopy is the first-choice technique for unequivocal structural assignment of organic, organometallic, and inorganic material in solution as well as in solid state. Besides that, NMR is widely applied to evaluate the dynamics of molecules in solution, as a tool in drug discovery to establish the binding site of study molecules in a target protein, to determine the stability of n…
(Only some records are available in English at this moment)
The technical reserve for research, granted by FAPESP, concerning the year of 2022 goals of applicaton were approved by the Congregation of the Institute of Chemisty on September 28, 2022 and are described below: maintenance/repair of multi-user institucional equipments / complementation of the Research Labs structured cabling construction / consumables for multi-user institucional e…
The purpose of the application of the technical reserve for research granted by FAPESP for the year 2021 was approved by the Institute of Chemistry Congregation on September 30, 2021 as described below:- Maintenance / repairs of institutional multi-user equipment;- Electrical adjustments in order to tranfer the FRX equipment to the DRX lab;- Complement of the structured cabling constructi…
Since most of the adverse effects are dose-related, ²-lactams have been the drug of choice for the treatment of bacterial infection. However, the misuse of these antimicrobial drugs speeded up the emergence of drug-resistant bacteria. It is important to emphasize that 9 of the 12 most dangerous families of bacteria, data released by WHO, has the presence of ²-lactamase as the main mechani…
(Only some records are available in English at this moment)
Nuclear Magnetic Resonance (NMR) is a spectroscopic technique that stands out for its spectra' wealth of structural information. It has recently been used in reaction monitoring, aiming to elucidate reaction mechanisms by obtaining kinetic profiles, since its understanding is fundamental for the improvement of industrial processes and understanding of biological systems. Reaction monitori…
This study explores the intramolecular coupling of various ortho-fluorophenols with cyclohexene oxide via one-pot methodology under basic conditions. Optimization includes tests with different bases, solvents and temperatures. Reaction products will be characterized experimentally, and theoretical analysis are aimed to identify the most favourable mechanistic pathway.
Heterocyclic rings constitute a large part of the vital molecules for life, participating directly in the formation of DNA and RNA, or participating in the maintenance of life through the incorporation of these rings in the structure of molecules with pharmacological properties. Among them, the purine, pyrimidine and pyridine rings stand out, which have several applications to be explored…
(Only some records are available in English at this moment)
The purpose of this research is to employ the one-pot methodology for the synthesis of benzoxazines through the combination of epoxides and anilines, aiming to compare the relationships between the contribution of stereoelectronic effects and the reaction kinetics of the total synthesis, while also serving as an alternative to the classical routes of obtaining these heterocycles through m…
Enantiomers are isomers that have the same molecular formula but are non-superimposable mirror images of each other due to the presence of an asymmetric carbon. They can interact differently in the human body or other systems, making their separation crucial, as one may be medicinal and the other toxic or inactive.Nuclear Magnetic Resonance (NMR) stands out for elucidating these compounds…
It is proposed to investigate the stability of non-classical carbocations formed by the opening reaction of alpha-pinene oxide in acidic medium in solvents of different polarities and at different temperatures. The structures and stability of the possible carbocations (Scheme 1) will be experimentally determined indirectly through the unequivocal determination of the structures and propor…
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Substitution reactions on aromatic rings, such as electrophilic (SEAr) and nucleophilic (SNAr) substitutions, have been widely studied due to their significant synthetic importance. Findings indicate that Meisenheimer intermediates in SNAr reactions are sometimes energetically too unstable, suggesting that in these cases a one-step, non-concerted mechanism would prevail, in which the C-F …
NMR is a powerful technique for various investigations, such as structural analyses, quantification, and molecular dynamics of organic compounds. DOSY experiments have been applied in several areas of science, ranging from the identification to the quantification of compounds in a mixture based on diffusion coefficient measurements without the need to physically separate the compounds. En…
The fluorine atom has been the centre of attention of multiple studies in diverse areas, and it is not different within the NMR area. Fluorine is one of the most abundant atoms on the earth surface, however, the interest on it is due to the modifications that its incorporation on organic molecules provides to their chemical and physical properties, lipophilicity, basicity, permeation of c…
Enantiomers are chiral molecules that are specular mirror images of each other but cannot be superimposed. These compounds have gained attention for their applications in various fields, including pharmaceuticals, agriculture, and food. The importance of enantiomers is due to their distinct interactions with other chiral molecules, which can result in different biological or pharmaceutica…
(Only some records are available in English at this moment)
| 5 / 5 | Ongoing grants |
| 12 / 9 | Completed research grants |
| 8 / 8 | Ongoing scholarships in Brazil |
| 21 / 17 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 7 / 7 | Completed scholarships abroad |
| 54 / 47 | All research grants and scholarships |
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