Nadia Monesi

• Abstract

  Sciarid DNA puff genes are amplified and expressed in a developmentally regulated manner in the salivary gland in response to the increase in ecdysone levels that precede metamorphosis. Data derived from functional studies in the model organism Drosophila melanogaster revealed the existence of cis-regulatory modules that drive gene expression in the salivary gland and the ring gland in th…

  The dipteran protoracic glands: morphological, genomic and functional studies in the dipteran B. hygida and D. melanogaster, AP.R
• Functional characterization and bioinformatics analysis of the bhc4-1 ring gland enhancer in transgenic drosophila., AR.EXT
• 1 410bp promoter fragment of the dna puff bhc4-1 gene is sufficient to maintain the temporal regulation of transcription in the salivary gland of drosophila early prepupae., AR.EXT

• Abstract

  The DNA puff C4 BhC4-1 gene of Bradysia hygiene is amplified and expressed in a regulated manner in two larval tissues, the prothoracic gland, and the salivary gland. Functional studies in Drosophila melanogaster revealed that the molecular mechanisms that regulate BhC4-1 expression are conserved in D. melanogaster and resulted in the identification of cis-regulatory modules that regulate…

  Characterization of the BhC4-1-lacZ mRNA pattern of expression in embryos of the (-824/-187), (-488/-187) and (-850/+40) series in D. melanogaster transgenic lines, BP.IC

• Abstract

  Our laboratory investigates the molecular mechanisms that promote developmentally regulated patterns of gene expression in eukaryotes. As a model, we employ the BhC4-1 DNA puff gene, which is amplified and expressed in a developmentally regulated manner at the end of the fourth larval instar of B. hygida. The functional analyses of the BhC4-1 promoter region lead to the identification of …

  In vivo analysis of the GFP pattern of expression driven by the BhC4-1 ring gland enhancer at the end of the embryonic development in D. melanogaster transgenic lines, BP.IC

• Abstract

  Our laboratory investigates mechanisms controlling gene expression in metazoans. As a model we employ the DNA puff gene BhC4-1, which is expressed at the end of the larval development of the sciarid Bradysia hygida. Functional assays in the model organism Drosophila melanogaster led to the identification of a salivary gland 129 bp (-186/-58) enhancer in the BhC4-1 promoter. Although the d…

  Analysis of the interaction between the E74A transcription factor and the regulatory region of the D. melanogaster CGs 7599 and 7336 using trans-activating assays in yeast, BP.IC

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