CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Bauru. Faculdade de Ciências (FC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Quimica from Universidade Presbiteriana Mackenzie (1994), bachelor's at Licenciatura curta em matematica e ciëncias from Universidade Camilo Castelo Branco (1989) and doctorate at Chemistry from Universidade de São Paulo (2000). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects: mieloperoxidase, neutrófilos, peroxidases, melatonina and quimiluminescencia. (Source: Lattes Curriculum)
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Those who work in research and development in the biomedical area are constantly faced with the need to search for the appropriate fluorescent marker for the cellular process under study. Cell signaling pathway markers, probes for membrane potential in mitochondria, labeled nucleotides, probes for reactive oxygen species, are some examples of a growing universe of fluorescent probes conju…
Detection, monitoring and quantification of molecular processes in simple systems, such as biochemical reactions in isolated systems, or complex ones, such as those occurring within cells or supramolecular systems, occurs by contrasting between what is wanted and what is not wanted to see. In other words, by increasing the signal to noise ratio. In this scenario, fluorescence-based techni…
Mounting evidence has demonstrated the role of hypohalous acids as hypochlorous acid (HOCl) and hypobromous acid (HOBr) as agents involved in biomolecules degradation. Indeed, the identification of biomarkers as chlorotyrosine and HOCl and HOBr modified proteins and nucleic acid has been widely demonstrated and correlated with pathologies as Alzheimer`s disease, Parkinson`s disease, chron…
Mounting evidence has demonstrated the role of hypohalous acids as hypochlorous acid (HOCl) and hypobromous acid (HOBr) as agents involved in biomolecules degradation. Indeed, the identification of biomarkers as chlorotyrosine and HOCl and HOBr modified proteins and nucleic acid has been widely demonstrated and correlated with pathologies as Alzheimer`s disease, Parkinson`s disease, chron…
(Only some records are available in English at this moment)
Modern biomedical research requires accurate fluorescent markers to study cellular processes, such as signaling pathways and reactive oxygen species (ROS). Fluorescent probes are essential for detecting biomolecules, monitoring enzymatic reactions, and identifying changes in microenvironments. They are sensitive to the physicochemical characteristics of the medium, altering their quantum …
The N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) is a compound derived from melatonin (MEL), generated from the oxidative cleavage of the pyrrolic nucleus via enzymatic, pseudo-enzymatic and nonenzymatic pathways. As MEL, AFMK is also an excellent antioxidant, being a great hydroxyl radical (*OH) scavenger and capable of inhibiting the production of pro-oxidant enzymes, pro-inflammatory…
The human serum albumin, HSA, is a major protein constituent from blood plasma. Among its functions, it highlights its performance in the transport of drugs. This property is particularly relevant in the context pharmacokinetic, since the HSA-drug interaction may interfere with the bioavailability of the drug in the body, affecting its therapeutic action. Therefore, evaluate the interacti…
Helicobacter pylori is one of major cause of chronic gastritis and peptic ulcer disease, increasing the probability of the onset of stomach cancer if the infection is left untreated. Although the mechanism involved in gastric inflammation by this bacterium is not fully understood, it is known the important role of reactive oxygen species (ROS) produced by polymorphonuclear neutrophils (PM…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 7 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 10 / 5 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 20 / 12 | All research grants and scholarships |
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