He is graduate at Chemistry from Universidade Estadual de Campinas (1992), master's at Chemistry from Instituto Militar de Engenharia (1995) and Ph.D. at Chemistry from Universidade de São Paulo (2000), besides 2 postdoctoral stages - Universidade de São Paulo and Barcelona Biomedical Research Park - Spain (2010). Currently, is Associate Professor 3 at the School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo - FCFRP / USP, since 2007, where he teaches 3 courses of Graduation and 2 of Post-Graduate. In research, works in the area of Medicinal Chemistry, with emphasis on molecular modeling and QSAR in drug design, including additional enzymatic activity assays with ligands of different therapeutic targets, particularly in cancer, Alzheimer's disease, leishmaniosis and inflammatory diseases. He is Principal Investigator of a CPA/CENTRO DE PESQUISA APLICADA EM INOVAÇÃO E SUSTENTABILIDADE DA CITRICULTURA since 2024.He was Director and Vice-Director of two International projects funded by FAPESP and CNPq, as welll as one of the principal investigators (PI) of International project in collaboration with the Nottingham University (PROGRAMA CAPES/UNIVERSIDADE DE NOTTINGHAM - SELEÇÃO DE PROJETOS ESPECIAIS DE PESQUISA EM DRUG DISCOVERY). He is also one of the investigators of the Center for Research in Inflammatory Diseases -CRID, FAPESP, as well as of the Medicinal Chemistry Open Acess, SGC-UNICAMP (The Structural Genomics Consortium), and researcher of a current FAPESP project in phytopathology. With the private sector, it has established and maintains a University-Company partnership, in the form of scientific advice to assess the toxicological potential of compounds of agrochemical interest, through QSAR (Quantitative Structure-Activity Relationships) and QSTR (Quantitative Structure-Toxicity Relationships) studies. He has 2 patent and 241 publications, including 181 papers and 56 chapters of Medicinal Chemistry and related, as well as he is Editor/coeditor of 4 international books in the field of Medicinal Chemistry. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
São Paulo's citrus industry is the most advanced in the world in terms of productivity, fruit and orange juice quality, research and development, technology transfer and sustainability. The productive strength of this important agribusiness chain in São Paulo results in significant economic, social and environmental values. However, the competitiveness and economic, social and environment…
Citrus canker, mainly caused by the bacterium Xanthomonas citri subsp. citri (XAC), is one of the most important citrus diseases, with a significant impact on the Brazilian economy. Studies of comparative proteomic analysis of the surface of infecting and non-infecting cells of XAC carried out with the collaborating group at the Laboratory of Biochemistry and Applied Molecular Biology (LB…
Inflammatory diseases are a complex and heterogeneous group of diseases that affect more than 10% of the word population. The current options for the treatment of these diseases are still limited and in some cases, inefficient due to limited understanding of the mechanisms underlying these diseases. The development of translational research by a center that can generate scientific knowled…
Neglected tropical diseases are a subset of infectious diseases reaching the poorest populations, most notably Chagas disease, African Trypanosomiasis and Leishmaniasis. The investment in the discovery of new drugs for these diseases is far below what is necessary, in the specific case of Leishmaniosis, the drugs that are commercially available in addition to the high cost, have undesirab…
Many of the discoveries from the rapidly expanding genomic sciences are not effectively utilized in medicine, agriculture and industry. This is partly because of the disconnection between scientists in different disciplines, and because much of the translational research done in both industry and academia is patent-protected and not published in a timely manner. This INCT proposal address…
(Only some records are available in English at this moment)
Cardiovascular diseases result from atherosclerotic lesions andaccount for 31% of world mortality. One of the biggest risk factors foratherosclerosis is smoking, which accelerates the atherogenic process by activatingaryl hydrocarbon (AhR) receptors by smoke contaminants from thecigarette. These receptors belong to the bHLH / PAS protein superfamily andinduce the expression of pro-atherog…
Some of the main therapeutic targets previously selected for the design of drug candidates in inflammatory diseases will be investigated with the use of different methodologies of Computational Medicinal Chemistry. The candidate has experience and he will work with ligand- and structure-based drug design (of the targets here investigated). (AU)
Cardiovascular diseases result from atherosclerotic lesions and account for 31% of the world mortality. A major risk factor for atherosclerosis is smoking, which enhances the atherogenic process upon the activation of aryl hydrocarbon receptors (AhR) evoked by cigarette smoke contaminants. These receptors belong to the bHLH/PAS protein superfamily and induce the expression of pro-atheroge…
(Only some records are available in English at this moment)
In this project, it is proposed the development and validation of an algorithm for finding bioactive conformations using GRIND and GRIND-2 descriptors, which will allow 3D-QSAR models based on conformations of maximum similarity of a series of compounds, with high chemical information and high predictive power, independent of the degree of freedom, in a semi-automated, fast and reliable p…
| 3 / 3 | Ongoing grants |
| 7 / 6 | Completed research grants |
| 14 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 25 / 20 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID