Paulo César Maiorka

• Abstract

  In the last years, a great majority of knowledge regarding the pathological events and immune response in infectious diseases was obtained from mouse models. Equid herpesvirus type 1 (EHV-1) is a potential emerging pathogen which is recognized worldwide as a cause of neurological disease in equine. However, a fatal and acute meningoencephalitis associated with extensive neuronal necrosis …

  Characterization of inflammatory response in the central nervous system in mouse models of viral and protozoan infection, AP.R

• Abstract

  Animal models in laboratory species are fundamental for coprehension of pathologic processes that involve experimental infection. Encephalitis are severe pathologic processes, immune and inflammatory responses are poorly understood and can participate in the pathogenesis of these diseases. Identification of patterns or markers of immune and inflammatory response are detrimental to compre…

  Identification of markers of imune and inflammatory response in experimentally induced viral encephalitis in a murine model, AP.R

• Abstract

  Veterinary Forensics is a new area of work for veterinarians. This is an important link between Law and Medical Sciences. Forensics is divided in Tanatology, Traumatology and Forensic Pathology and Toxicology. To prepare Forensic Expert Report is necessary to be clear and focused. Many special laboaratory are neede to support the Witness Testimony Report, and there are few studies and sci…

  Study of pathological alterations in situations of expert witness examination of animals, AP.R

(Only some records are available in English at this moment)

• Abstract

  Carbamates are acetylcholinesterase inhibitors with many different formulations and uses. Aldicarb and carbofuran, originally formulated for agricultural use, are frequently employed to cause abortions, homicides, suicides and intoxications of domestic and wild animals. They are known as "small lead" due to its dark granular presentation, are offered to animals with food (bait) in a singl…

  Detection and analysis of the carbamate distribution by DESI mass spectometry in formalin fixed and paraffin embedded tissues of intoxicated animals, BP.MS

• Abstract

  Equid herpesvirus type 1 (EHV-1) is a potential emerging pathogen which is recognized worldwide as a cause of neurological disease in equine. However, a fatal and acute meningoencephalitis associated with extensive neuronal necrosis caused by EHV-1 have been reported in other animal species. The morphological changes in the central nervous system (CNS), as well as the disease outcome in t…

  Characterization of immune response in the central nervous system of mice infected with highly neurovirulent strains of Equid Herpesvirus type 1, BP.PD

• Abstract

  Neospora caninum is an apicomplexan protozoan, known worldwide as a important causative agent of abortions in livestock, especially dairy cattle, causing only in Brazil estimated losses of $ 51.7 million annually in dairy farms, and $ 101 million in beef cattle. In 2013, considering 10 countries, annual losses reached an estimated value of $ 1.298 billion. Clinically neosporosis is manife…

  Isolation and pathogenicity evaluation of a new Neospora caninum strain from naturally infected goats, BP.DR

(Only some records are available in English at this moment)

• Abstract

  Equid herpesvirus type 1 (EHV-1) is an emerging pathogen that causes a neurological disease in horses, which is characterized by a myeloencephalitis with vasculitis and thrombosis. However, many cases of an acute and fatal meningoencephalitis with severe neuronal necrosis have been reported in other animal species. Mouse models of EHV-1 infection have been developed in attempt to elucidat…

  Inflammatory response in the central nervous system of mice experimentally infected with Equid Herpesvirus type 1, BE.EP.PD

• Abstract

  Neospora caninum is considered the major agent that causes abortions in ruminants worldwide. Since the description of the parasite in 1988, a lot of studies show clinical and experimental results, both in-vivo and in vitro, that demonstrates different biological behavior of parasite isolates, suggesting that different strains, causing neosporosis, may have different virulence factors. The…

  Microsatellite genotyping of Neospora caninum strains from naturally infected goats, BE.EP.DR

• Abstract

  The vesicular stomatitis virus (VSV) is a well known virus that causes encephalitis in mice when inoculated intranasally. The deer mouse, a native New World rodent, has been used as a model for VSV infection. VSV neuropathogenesis in deer mouse is similar as those observed in others rodent species, and, when inoculated intranasally, the VSV can spread throughout the central nervous system…

  Chemokine responses in brain of deer mouse (Peromyscus maniculatus) experimentally infected with vesicular stomatitis virus, BE.EP.DR