CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Psicologia (FFCLRP) from Universidade de São Paulo (1994), master's at Pharmacology from Universidade de São Paulo (1998) and ph.d. at Pharmacology from Universidade de São Paulo (2003). Has experience in Psychology, acting on the following subjects: nmda receptor, stress, restraint stress, hippocampus and ansiedade. (Source: Lattes Curriculum)
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Abandonment, neglect and abuse in childhood and adolescence are risk factors for the development of psychiatric disorders. Studies in animal models and humans suggest that such susceptibility is related to long-lasting changes in the hypothalamic-pituitary-adrenal (HHA) axis, such as hypercortisolism, axis hyperactivity and reduced negative feedback, possibly due to the imbalance between …
Stress has been considered as one of the etiological factors in Psychiatric Disease, since it induces behavioural, neuroendocrine and cardiovascular changes, leading to an arousal state which in turn can be observed by changes in behaviour and central nervous system functioning. Such responses are coordinated by several brain structures such as prefrontal cortex (PFCx), hippocampus (dH), …
O objetivo do evento é apresentar um panorama geral da influência da teoria de Deakin e Graeff (proposta em 1991) ao longo de 25 anos de sua publicação, sobre a literatura científica no campo de Transtornos Psiquiátricos, principalmente no que se refere aos Transtornos de Ansiedade e de Humor. Tal proposição teórica, que já possui mais de 600 citações na literatura, resultou na publicação…
Major Depression is a complex disease which etiology has been associated to a central serotoninergic disfuncion and/or exposure to inescapable/uncontrollable stress. On the other hand, adaptation to stressful situations involves changes in the functioning of serotoninergic systems mediated by different receptors. Serotoninergic projection from the Median Raphe Nucleus (MnRN) to the Dorsal…
(Only some records are available in English at this moment)
Stress is an important etiological factor in the development of psychiatric disorders such as major depression. Exposure to stressors leads to behavioural and endocrine changes, which are not observed when animals are raised and maintained in environmentally enriched conditions. On the other hand, an enriched environment promotes significant neuroprotective effects, with positive neuropla…
Serotonin (5-HT) is a neurotransmitter that regulates various physiological and behavioral processes and is involved in adaptation to aversive events, such as forced detention and forced swimming. Serotonergic dysfunctions are associated to various disorders, such as depression. The serotonergic projections of the median raphe nucleus (MRN) towards the dorsal hippocampus, would be respons…
Existing theories regarding the cause of depressive disorders focus on monoamines, specially the role of serotonin (5-HT). Evidences support the hypothesis that serotoninergic neurotransmission is not only involved with the process of adaptation to aversive events, but it is also sensible to different kinds of stressors. The literature provides evidence that the serotonin pathway connecti…
Serotonin (5-HT) is a neurotransmitter that regulates diverse physiological processes are involved in the adaptation to aversive events, such as forced immobilization. Serotonergic projections that depart from the Median Raphe Nucleus (NMnR) toward the Dorsal Hippocampus, would be responsible for adapting to stress. The 5-HT7 receptor is a 5-HT postsynaptic present in several brain struct…
(Only some records are available in English at this moment)