Victor Marcelo Deflon

• Drug Discovery and Therapy World Congress 2013, AR.EXT

• Abstract

  We propose the creation of the appropriate infrastructure, at the USP São Carlos Institute of Chemistry, for the use of single-crystal X-ray crystallography, applied to small molecules as well as to proteins. To that end, we are requesting the acquisition of a single-crystal X-ray diffractometer with high-intensity copper and molybdenum X-ray tubes. There are currently no such diffractome…

  Acquisition of a single-crystal X-ray diffractometer for the structural analysis of small molecules and proteins , AP.EMU
• Synthesis and Structural Characterization of Transition Elements Complexes with Potential Medicinal Application, AP.R

• Abstract

  One of the big challenges in inorganic medicinal chemistry is to obtain more specific drugs and with high activities to different diseases. In this aspect, the calculated properties with the use of computational quantum chemistry can lead to the design of new candidate drugs, avoiding the experimental massive costs. In this way, the quantum chemical methods can provide an important contri…

  Characterization of metal complexes with medicinal applications: a spectroscopy and a quantum chemical investigation, BP.PD

• Abstract

  The use of inorganic compounds in the treatment of infectious and parasitic diseases is becoming increasingly common, since the microorganisms that cause these diseases develop resistance to traditional treatments, that are generally based in the use of organic compounds, such as isoniazid, used in the treatment of tuberculosis.The complexes of rhenium and vanadium have biological propert…

  Complexes of vanadium (+ IV and + v) and rhenium (+V) with bioactive ligands: synthesis, characterization and biological studies aiming obtaining potential anti-Mycobacterium tuberculosis and antiparasitic agents, BP.MS

• Abstract

  This project consists on the synthesis and structural characterization by both experimental and molecular modeling of new complexes based on Au(III), Au(I), Re(V), Re(I), Tc(V) and Tc(I) as metal centers, with bioactive ligands of thiosemicarbazone type, and co-ligands of phosphine, halides and carbonyl types, in the interest of obtaining new agents for studies of activities against tuber…

  Au, Re and Tc thiosemicarbazones complexes of interest in the development pharmaceuticals or radiopharmaceuticals for diagnostic or therapy, BP.PD

(Only some records are available in English at this moment)