CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1987), master's at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1993) and doctorate at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1997). Has experience in Odontology, focusing on Odontopaediatrics, acting on the following subjects: dentina, citotoxicidade, células odontoblastóides, adesivos dentinários and cytotoxicity. (Source: Lattes Curriculum)
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Although there are dental materials with clinical acceptable performance when applied on direct contact with the pulp tissue, these calcium hydroxide-based materials cause, initially, tissue necrosis and cell death. The growth in the knowledge of pulp biology plus the remarkable progress in the field of tissue engineering and biotechnology have made possible the development of biocompatib…
Two main challenges to establish more efficient and stable resin-dentin bonds are: (1) infiltrating the etched dentin with more hydrophobic monomers and (2) making the collagen resistant to degradation. Current researches on adhesion are designed to better understanding how to overcome these challenges. By developing the experiments included in the present project, we aim to investigate t…
Despite the fact that there are a few studies investigating the effects of different light sources on the tissue's dynamic, little is known about the action mechanism of cellular irradiation with light emitting diodes (LED) on the biomodulation of inflammation, especially for the pulp tissue. Thus, the aim of the present study will be to investigate the effect of an 855 nm wavelength LED …
(Only some records are available in English at this moment)
Reverting the pro-inflammatory into a pro-regenerative environment remains a challenge in Vital Pulp Therapy. Bioactive molecules have been widely explored for endodontic regeneration in degenerative inflammatory environments, i.e., in adverse pulp conditions. Flavonoids (natural phenolic compounds) have several well-established biological/pharmacological activities, including antioxidant…
Reverting the pro-inflammatory into a pro-regenerative environment remains a challenge in Vital Pulp Therapy (VPT). Biomaterials that mimic the native extracellular matrix have been widely explored for endodontic regeneration, and their functionalization with bioactive molecules makes them capable of modulating dentinogenesis in degenerative inflammatory environments, i.e., in adverse pul…
The bioactive effects of restorative materials incorporated with surface pre-reacted glass-ionomer (S-PRG) fillers are attributed to the eluted ions. For this reason, the eluate obtained from S-PRG fillers has been investigated for several therapeutic applications aimed at increasing the longevity of restorations and reducing the progression of caries and erosion lesions. However, the eff…
The philosophy of the contemporary dentistry encompasses the minimal intervention to manage enamel and dentin caries. Among the minimal intervention procedures, the use of silver diamine fluoride (SDF) has been indicated to halt the progression of caries lesions, including those extending into the inner half of the dentin, providing there are no clinical and radiographic signs of irrevers…
Treatment of pulp exposure in permanent teeth is still a challenge for clinicians due to available materials limitations, which often imply failure. Advances in bioengineering have permitted the reformulation of therapies that guide tissue repair from specific stimuli on cells present in damaged tissue. Among the strategies, nanofibrous scaffolds have highlighted the regeneration of crani…
The pulp tissue of human teeth is a rich source of undifferentiated mesenchymal stem cells and, therefore, has a great reparative potential. Despite that potential, the direct pulp capping materials currently used to promote tissue repair, mostly based in calcium hydroxide, cause superficial necrosis of the pulp, intense cell death and inflammation. This mechanism of action does not respe…
(Only some records are available in English at this moment)
This project aims to investigate the permeability of mineralized and demineralized dentin against different solvents when used as carriers of hydrophobic monomers and elucidate the HEMA wet-bonding concept. Six hundred (600) sound human third molars will be collected and used for the production of powdered dentin. The dentin powder (25 cm3) will be placed in a glass column (30.0 cm x 1.0 …
This project aims to investigate the permeability of mineralized and demineralized dentin against different solvents when used as carriers of hydrophobic monomers and elucidate the HEMA wet-bonding concept. Six hundred (600) sound human third molars will be collected and used for the production of powdered dentin. The dentin powder (25 cm3) will be placed in a glass column (30.0 cm x 1.0 …
The search for biomaterials that promote the regeneration of dental pulp tissue has been the subject of research in tissue engineering. Research on scaffolds, matrices formed by natural or synthetic polymers, aim to promote recovery of the tissue that suffered aggression. Chitosan, a natural polymer, has been evaluated for its bio-stimulatory and bio-reparative activities, with potential …
(Only some records are available in English at this moment)
| 9 / 8 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 31 / 27 | Completed scholarships in Brazil |
| 5 / 5 | Completed scholarships abroad |
| 48 / 43 | All research grants and scholarships |
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