Abstract
Application of technical resource reservation for improving institutional research activities at the Institute Butantan (AU)
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
Biomedical Scientist from the University of Santo Amaro (1996), with a Masters degree (2000) and PhD (2004) in Pharmacology from the Institute of Biomedical Sciences, University of São Paulo (ICB/USP), and a Postdoctoral Fellowship in Cell and Developmental Biology (USP, 2011). She has been a Scientific Researcher at the Butantan Institute since 2004, working at the interface of immunometabolism, toxinology, and the tumor microenvironment. She coordinates the Crotoxin, Matrix and Immunometabolism Research Group, investigating the immunomodulatory effects of crotoxin on macrophages, tumor cells, and biomimetic 3D models. She develops in vitro three-dimensional platforms to study cell interactions in oncology and inflammation. Since 2018, she has served as Director of the Scientific Development Center and Vice-President of Research and Graduate Studies at the Butantan Institute. She coordinates CeVIVAS (Center for Viral Surveillance and Serological Evaluation) and the EMU Technological Project: Acquisition of a High-Performance Computing System for Health and Life Sciences. She is a member of the SARS-CoV-2 Genomic Sequencing Network in the State of São Paulo. Her work is strongly focused on biotechnology applied to public health, particularly in the development and validation of RT-PCR platforms, microneutralization assays, and multiplex tests for arboviruses and respiratory viruses. She led the Strategic Molecular Diagnostic Laboratory at the Butantan Institute during the COVID-19 pandemic and currently contributes to genomic surveillance networks. She takes part in national and international collaborative networks in public health and coordinates institutional partnerships with public laboratories, companies, and research centers. She is an evaluator for INEP/MEC (SINAES), a reviewer for international journals. She currently serves on the Boards of Directors and Trustees of the Butantan Institute and the Butantan Foundation, respectively, and contributes to advisory committees of major research funding agencies. She is a full professor in the Graduate Programs in Toxinology and Biotechnology at the Butantan Institute, and also teaches in the Departments of Pharmacology and Immunology at the University of São Paulo (ICB/USP). Awarded by CNPq with 2nd place nationally in the 8th "Scientific Initiation Outstanding Research Award" (2010), she has authored over 100 articles in peer-reviewed international journals, supervised students at all academic levels (Masters, PhD, and postdoctoral), holds two patent applications, and plays a prominent role as a scientific reviewer (CNPq, FAPESP). She coordinates research projects supported by FAPESP, FINEP, and private companies, totaling over R$ 24 million in funding. ORCID: 0000-0001-6257-3531 (Source: Lattes Curriculum)
Articles published in Pesquisa FAPESP Magazine about the researcher: |
Butantan’s dengue vaccine is 80% effective |
La vacuna contra el dengue producida en Brasil por el Instituto Butantan de São Paulo posee una eficacia del 80 % |
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News published in Agência FAPESP Newsletter about the researcher |
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Application of technical resource reservation for improving institutional research activities at the Institute Butantan (AU)
In this project, we will gather skills from several researchers in the areas of Health Science, Biological Science and Computer Science aiming at the area of Life Sciences and high performance computing (HPC). The advancement of biotechnology and molecular technologies, integrated with developments in the latest technologies in the area of Bioinformatics and Computational Biology, has ope…
Vaccination is the touchstone of public health policies. The history of vaccination shows that vaccines have been empirically developed; therefore, many studies are still needed for the continuous development of this biological product. The effectiveness of vaccines is evaluated through the reduction of the infection or illness among vaccinated individuals, and it is influenced by many fa…
application of technical resource reservation for improving institutional research activities at the Institute Butantan (AU)
(Only some records are available in English at this moment)
The project "Impact of different dengue genotypes on the pathophysiology and severity of the disease: a multi-omics approach" aims to understand the changes in the dengue pathogen-host interaction, investigate whether there is any genetic factor, whether from the host or the virus, responsible for the severity of the disease, and understand if there are any proteins, peptides, or smaller …
Macrophages (MØ) are cells with high plasticity that can be reprogrammed into two distinct phenotypes - MØ M1 (pro-inflammatory) and MØ M2 (anti-inflammatory) - according to the nature of the disorder detected in the organism. Experimentally, it is possible to induce reprogramming of macrophages to M1 and M2 and the functional and metabolic status of both phenotypes have already been char…
(Only some records are available in English at this moment)
3 / 3 | Ongoing grants |
13 / 11 | Completed research grants |
2 / 2 | Ongoing scholarships in Brazil |
10 / 6 | Completed scholarships in Brazil |
28 / 22 | All research grants and scholarships |
Associated processes |