Hudson de Sousa Buck

• Abstract

  The kallikrein-kinin system has been associated with inflammation and immunogenic responses in the nervous and peripheral systems by activation of two receptors, B1 and B2. The B1 receptor is absent or poorly expressed under physiological conditions, its overexpression occurs during tissue injury or in the presence of cytokines. The B2 receptor is constitutive and mediates most biological…

  Study of the cell survival modulation by B2 receptor for bradykinin and its impact on neuroinflamation in organotypic hippocampal culture of transgenic mice for Alzheimer's Disease, AP.R

• Abstract

  The Kallikrein-Kinin System (KKS) has been associated to inflammatory and immunogenic responses in the peripheral and central nervous system by the activation of two receptors, namely B1 receptor and B2 receptor. The B1 receptor is absent or under-expressed in physiological conditions, being up-regulated during tissue injury or in the presence of cytokines. The B2 receptor is constitutive…

  Study of the neuroprotective role of kinin B2 receptor in the Alzheimer's Disease, AP.R

• Abstract

  Since the beginning of the twentieth century authors such as Barker have proposed explanations for the fetal origin of coronary heart disease in adulthood, which has received support from researchers such as Brenner. He described the association between the systemic hypertension and the reduced number of nephrons caused by low weight at birth or prematurity. These may be responsible for h…

  Study of markers of nephropathy in adult rats with low weight at birth, AP.R

(Only some records are available in English at this moment)

• Abstract

  The kallikrein-kinin system has been associated with inflammation and immunogenic responses in the nervous and peripheral systems by activation of two receptors, B1 and B2. The B1 receptor is absent or poorly expressed under physiological conditions, its overexpression occurs when a tissue injury occurs or in the cytokines presence.. The B2 receptor has constitutive expression and mediate…

  Study of the cell survival modulation by B2 receptor for bradykinin and its impact on neuroinflamation in organotypic hippocampal culture of transgenic mice for Alzheimer's disease, BP.PD

• Abstract

  The Kallikrein-Kinin System (KKS) has been associated to inflammatory and immunogenic responses in the peripheral and central nervous system by the activation of two receptors, namely B1 receptor and B2 receptor. The B1 receptor is absent or under-expressed in physiological conditions, being up-regulated during tissue injury or in the presence of cytokines. The B2 receptor is constitutive…

  Bradykinin B2 receptor neuroprotection role in Alzheimer's Disease, BP.PD
• Evaluation of the neurodegeneration promoted by the chronicle infusion of human amiloide beta peptide, in kinin B1 or B2 receptors knock-out mice, BP.IC

• Abstract

  In the NTS or in the paratrigeminal nucleus of conscious normotensive (NWR) or hypertensive rats (SHR), bradykinin induces a pressor effect through the stimulation of B2 receptors, and the SHR showed a increased sensibility to BK and almost a doubled density of B2 receptor expression in these nuclei. The B I receptor is generally under expressed in normal conditions. The objective of this…

  Autoradiographic analysis of kinin receptor expression in the normotensive and hypertensive human brainstem, BE.PQ