CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Instituto de Biociências (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduation at Ciências Biológicas from Universidade Estadual de Campinas (1994), master's at Immunology from Universidade Estadual de Campinas (1998) and doctorate at Genetics from Universidade Estadual de Campinas (2004). She is currently professor at Universidade Anhembi Morumbi. Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: oral tolerance, camundongos, aging, envelhecimento and cytokines. (Source: Lattes Curriculum)
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Introduction Literature data have shown that the consumption of dietary proteins may cause modulatory effects on the host immune system, process denominated oral tolerance by bystander suppression. It has been shown that the bystander suppression induced by dietary proteins can improve inflammatory diseases such as experimental arthritis. Here, we evaluated the effects of oral tolerance i…
The usual treatments for patients with non-small-cell lung cancer (NSCLC), such as advanced lung adenocarcinoma, are unspecific and aggressive, and include lung resection, radiotherapy and chemotherapy. Recently, treatment with monoclonal antibodies and biological inhibitors has emerged as an effective alternative, generating effective results with few side effects. In recent years, sever…
Colorectal cancer is considered a disease of the elderly population. Since the number of geriatric patients continues to rise, monoclonal antibody therapy is the most promising in recent research. Presently, the monoclonal antibodies most frequently used in the treatment of colorectal tumors are bevacizumab, cetuximab, panitumumab and ramucirumab. Bevacizumab is a monoclonal antibody th…
(Only some records are available in English at this moment)
The experimental colitis induced by 2,4,6 - Trinitrobenzenesulfonic acid (TNBS) is used for the study of colitis, since this model can generate lesions similar to those found on inflammatory bowel disease in humans. In this context, our group has developed strategies to understand the mechanisms that modulate the autoimmune responses in colitis, by using the adoptive transfer of dendritic…
Immune response in gastrointestinal trait usually results in pathogen elimination. However, dietary proteins as well as comensal microrganisms are tolerated antigens. Tolerance acquired by ingestion of proteins seems to depend on the generation of regulatory or supressor T cells, but dendritic cells (DCs) might be deeply involved in this process. Cytokines from Th1 or Th2 cells may influe…
| 8 / 6 | Completed research grants |
| 6 / 2 | Completed scholarships in Brazil |
| 14 / 8 | All research grants and scholarships |
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