CV Lattes
Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas- Modalidade Médica from Universidade Estadual Paulista Júlio de Mesquita Filho (1996) and ph.d. at Bioquímica from Universidade de São Paulo (2002). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects: unfolded protein response (upr), estresse do retpiculo endoplasmático, estresse oxidativo, proteína dissulfeto isomerase (pdi) and leishmania. (Source: Lattes Curriculum)
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Unfolded or misfolded protein accumulation in the Endoplasmic reticulum (ER) induces an adaptative cellular response known as Unfolded Protein Response (URP) consisting of a cell signaling cascade which integrates ER to nuclear gene expression (Schröder & Kaufman, 2005). Sustained UPR leads to ER Stress condition which is implicated in cell death in many pathophysiological conditions incl…
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