Pharm. D. by Centro Universitário Católico Salesiano Auxilium de Araçatuba (2014). He was a fellow of Scientific Initiation by CNPq/ PIBIC Reitoria UNESP and Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Master and PhD in Physiological Sciences by the Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas (UNESP Araçatuba). He was Visiting Associate at the Duke University, School of Medicine, Durham, North Carolina, U.S., during his PhD program. He has experience in Cardiovascular Physiology and Pharmacology, studying the mechanisms involved on reactive oxygen species production and nitric oxide bioavailibility on hypertension and sepsis. (Source: Lattes Curriculum)
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Nitric Oxide (NO) is the major vasodilator molecule in the body and it is synthesized by the NO synthase enzymes, and the isoform III or endothelial (eNOS) is the main responsible for the production of NO in the blood vessels. Increased production of Reactive Oxygen Species (ROS) by oxidative enzymes such as NOX enzymes can lead to oxidative stress and reduce NO bioavailability. We have r…
The chronic treatment with NADPH oxidase inhibitors reduces the SHR arterial pressure. Because it is the main superoxide anion source in the aorta, the activity of this enzyme is related with the decrease of the NO bioavailability. The purpose of this study will be to test the hypothesis that the treatment with apocynin (NADPH oxidase inhibitor) modifies the hypotensive effect of the acet…
Sepsis is a syndrome of physiologic, pathologic, and biochemical abnormalities induced by infection. The major cause of morbidity and mortality in sepsis is cardiac dysfunction. During sepsis, histones can be released into the circulation due to extensive inflammation and cellular death. Circulating histone levels are correlated to disease severity and the major mediator of myocardial dys…
| 2 / 2 | Completed scholarships in Brazil |
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CV Lattes
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