CV Lattes
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Universidade de São Paulo (USP). Escola Politécnica (EP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Andre Fabio Kohn holds a degree in Electrical Engineering from the University of São Paulo - EPUSP (1973), an MS in Electrical Engineering from EPUSP (1976) and a Ph.D. in Engineering from the University of California at Los Angeles - UCLA (1980), where he conducted research at the UCLA Brain Research Institute. In 1994 he conducted research at the National Institutes of Health (Bethesda), specifically at the NINDS, on human spinal cord physiology. He is a Professor of Biomedical Engineering at EPUSP, where he directs the Biomedical Engineering Laboratory (LEB /EPUSP). He has experience in areas related to Biomedical Engineering and Neuroscience, with emphasis on Human Neuroscience and Computational Neuroscience. His research nowadays if focused on postural control in humans, mathematical modeling and simulation of the neuromuscular system, neurophysiology of the human spinal cord. He was a member of the Advisory Committee for Electrical and Biomedical Engineering at CNPq, the Brazilian equivalent to the NSF. During his career at EPUSP, he taught courses on topics such as systems and signal theory, general neuroscience, human spinal cord neurophysiolçgy, digital signal processing, stochastics processes, pattern recognition, neural engineering, processing of random signals, biomedical signal processing. (Source: Lattes Curriculum)
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Mechanically evoked reflexes have been postulated to be less sensitive topresynaptic inhibition (PSI) than the H-reflex. This has implications on investigations ofspinal cord neurophysiology that are based on the T-reflex. Preceding studies have shownan enhanced effect of PSI on the H-reflex when a train of ~10 conditioning stimuli at 1Hzwas applied to the nerve of the antagonist muscle. …
The first objective of this study is the evaluation of the proprioceptive feedback associated with the ankle and at the same time verifying if its sensitivity can be increased by means of random electrical stimulation. Brain responses in humans to different angular variations in the ankle will be analyzed in an effort to provide objective estimates of the sensitivity and the dynamics to a…
(Only some records are available in English at this moment)
Large-scale computational models of the neuromuscular system have been shown to be very useful in the study of motor control in healthy subjects. However, these models have practically not been used for the study of neuromuscular pathologies. The present project intends to investigate pathologies that cause demyelination of the motor and sensory axons by means of a large-scale computation…
Transcutaneous spinal direct current stimulation (tsDCS) has been shown to modulate spinal excitability even though the underlying neural mechanisms are not known. To increase the knowledge about the plasticity of spinal cord circuitry by tsDCS, we will investigate the effects of stimulating an important neural circuit responsible for regulating the presynaptic inhibition (PSI) of soleus …
Women are frequently more fatigue resistant than men (women have longer time to task failure) during static contractions, such as the ones performed in postural tasks. The magnitude of presynaptic inhibition can potentially determine the time to task failure during static contractions. However, a sex difference in this mechanism is not known. Thus, the central aim of this project is to de…
(Only some records are available in English at this moment)
Neurophysiological changes have been associated to motor skill learning. For instance, following ankle force-matching practice, increased corticospinal excitability (assessed by Transcranial Magnetic Stimulation - TMS) and higher interaction between motor cortex and motoneurons (assessed by electroencephalography and electromyography) are observed. However, the corticospinal adaptation af…
The current project aims at examining reflex modulations during gait in human subjects. This study is an extension of an ongoing investigation on bilateral reflex modulation in seated humans. A complementary study on seated subjects, proposed for the second year of the fellowship, will be finished on the PD fellow's return from his internship in Japan. The main tool for studying changes i…
| 14 / 8 | Completed research grants |
| 24 / 16 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 40 / 26 | All research grants and scholarships |
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