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Universidade de São Paulo (USP). Instituto de Medicina Tropical de São Paulo (IMT) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Machado holds a medical degree from the Federal University of São Paulo (UNIFESP) (1979), a Master's Degree in Infectious and Parasitic Diseases from UNIFESP (1989) and a Ph.D. in Infectious and Parasitic Diseases from the University of São Paulo (USP) (1996). From 1998 to 2000, Dr. Machado occupied a postdoctoral position at the Clinical Virology Laboratory, University of Minnesota, MN, USA. She has developed her professional activities in the field of infections in hematopoietic stem cell and solid organ transplantation, including viral infections, respiratory virus infections, tropical and neglected diseases and vaccination of transplant recipients. Currently, Dr. Machado is a senior investigator at the Virology Laboratory of the Institute of Tropical Medicine, University of São Paulo School of Medicine (IMT-FMUSP). She is the coordinator of the Infectious Diseases Program at the Hematopoietic Stem Cell Transplant Unit of Amaral Carvalho Foundation in Jahu, SP. Dr. Machado has participated as council member of the International Immunocompromised Host Society (ICHS, 2008-2016) and Transplant Infectious Diseases, a section of The Transplantation Society (TID-TTS). Dr. Machado was the President of TID-TTS from 2017 to 2019. (Source: Lattes Curriculum)
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Aedes mosquitoes are well adapted in domestic environments and widespread in tropical regions. Since 2015, Brazil has been experiencing a triple epidemic of dengue (DENV), chikungunya (CHKV), and Zika (ZIKV) viruses. The last 2 viruses are likely following the path the first reports of Zika of DENV, which has been endemic in most parts of the country since the 1980s. Given this triple epi…
The cytochemistry Laboratory was created along with the HSCT program of the Amaral Carvalho Hospital for the realization of the CMV antigenemia technique. Since 2004, new diagnostic techniques were implemented to better assist the HSCT recipient, based on the results obtained in research projects approved by FAPESP. Thus, the following techniques were implemented: Indirect immunofluoresce…
CMV infection is an important complication of transplant recipients, especially in the context of hematopoietic stem cells (HSCT) and lung transplantation. The use of prophylaxis after lung transplantation and the pre-emptive therapy with ganciclovir (GCV), ie, the early introduction of GCV based on positivation of rapid diagnostic techniques (detection of pp65 antigenemia or PCR), signif…
(Only some records are available in English at this moment)
The main risk factor for tuberculosis (TB) reactivation in HSCT recipients is to live in regions with high endemicity. The incidence of TB in Brazil is 38.2 per 100,000 inhabitants per year. Post transplant immunosuppression favors the reactivation of latent TB infection (LTBI) and a higher incidence of tuberculosis is expected in this group of patients in comparison to general population…
Human metapneumovirus was first isolated in stored nasal aspirates from children with respiratory symptoms in the Netherlands by Van den Hoogen et al. (2001). Clinical findings were similar to those observed in children with RSV infection, ranging from mild symptoms such as fever, cough or coryza, to severe complications such as pneumonia or bronchiolitis. Since this preliminary report, o…
| 16 / 12 | Completed research grants |
| 15 / 2 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 32 / 14 | All research grants and scholarships |
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