CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1991), master's at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1996) and doctorate at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2000). Has experience in Odontology, acting on the following subjects: candida albicans, microondas, desinfecção, terapia fotodinâmica and resinas acrílicas. (Source: Lattes Curriculum)
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Antifungal resistance to conventional drugs has been a challenge in controlling fungal infections. Approaches that reduce extracellular polymeric substances weaken the biofilm structure, making it more susceptible to the action of antifungal therapies. Antimicrobial photodynamic therapy (aPDT) has been investigated for the control of Candida albicans biofilms and present promising results…
In this proposal we shall continue our efforts to generate cutting-edge science where fundamental and applied research will advance together in the field of optics. Our research program comprises three main thrusts: cold-matter physics, plasmonics and biophotonics, fields that linked by a common theme of light matter interaction. In parallel we shall advance fundamental understanding and …
The aim of the study will be to evaluate the efficacy of antimicrobial photodynamic therapy (aPDT) associated with DNase (DNase I) in the treatment of induced candidosis oral in mice infected with fluconazole-susceptible and resistant Candida albicans strains. Female mice (Swiss) approximately 5 weeks old will be immunosuppressed and inoculated with C. albicans (107 CFU / mL). The animals…
The widespread use of light emitting diodes (LED) as a light source for medical applications has caused concerns about the safety of this technology, especially when high energy radiation is used. Thus, the objective of this study is to evaluate the biological and antimicrobial effects of LED light at different wavelengths and light doses with the aim to provide new applications with grea…
This proposal is for the implementation of a National Institute with the clear objective of to continue performing fundamental science, but mainly to create a national network with high power to translate science and scientific skills in product and processes of high technological content in Optics. The main focus will be in the area of health and agriculture. Using the basic knowledge th…
(Only some records are available in English at this moment)
Antifungal resistance to conventional drugs is currently a challenge to control fungal infections. In this context, Antimicrobial Photodynamic Therapy (aPDT) has been investigated to control Candida albicans biofilms in order to inactivate microbial cells and weaken the Extracellular Matrix (ECM). Photodithazine (PDZ) is a Photosensitizer (PS), a second-generation e6 chlorin used in photo…
The challenge for fungal infection treatments today is resistance to conventional drugs. Thus, several studies are investigating new therapies that are effective in inactivating microorganisms. Studies using antimicrobial peptides (AMPs) have shown promising results with an emphasis on the control of bacterial and fungal infections. The objective of this study will be to evaluate the anti…
The fungus Candida albicans, in situations of imune imbalance in the host, can become an opportunist pathogen and cause infections. Due to the resistence that microorganism has developed to conventional drugs, antimicrobial photodynamic therapy (aPDT) has shown promising results as an alternative therapy. The aim of this study will be evaluate the induction ablity that aPDT has in develo…
The aim of the study will be to evaluate the efficacy of antimicrobial photodynamic therapy (aPDT) associated with DNase (DNase I) in the treatment of induced Candidosis Oral in mice infected with fluconazole-susceptible and resistant Candida albicans strains. Female mice (Swiss) approximately 5 weeks old will be immunosuppressed and inoculated with C. albicans (107 CFU/mL). The animals w…
(Only some records are available in English at this moment)
The aim of this project is to investigate the antimicrobial effect of salivary proteins and synthetic salivary antimicrobiol peptides (AMPs) against dual-species biofilms consisting of Candida albicans (ATCC 10231) and Streptococcus mutans (UA159) formed on acrylic resin. For this, the salivary proteins (Histatin 3; Histatin 5) and AMPs (DR9-RR14; RR14) will be individually adsorbed onto …
The polymicrobial nature of biofilms associated with oral diseases has increasingly been recognized. These biofilms, through cell-to-cell interactions, cell-extracellular polymeric substances, spatial organization, and biochemical and biophysical components, can modify the microbial virulence capacity. It has already been shown that the Candida albicans-Streptococcus mutans interaction ca…
Infections caused by Candida spp. biofilms are of great importance, especially in immunocompromised patients. The resistance of Candida spp. biofilms to medications may be associated with the protective effect of the extracellular matrix (ECM) components. Antimicrobial Photodynamic Therapy (PDT) and Sonodynamic Therapy (SDT) have been suggested as alternative treatments for the inactivati…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 12 / 8 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 35 / 19 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 54 / 34 | All research grants and scholarships |
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