CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Obtained a B.S. in Pharmeutical Sciences from the Federal University of Rio Grande do Norte, Brazil, in 2001. Completed, in 2003, a Master Degree Program in Sciences with focus on Pharmacology at the University of Sao Paulo, Brazil. In 2008, received a PhD degree also in Sciences (area: Pharmacology) from the same University (University of Sao Paulo). As a Pos-doc, was first trained in cerebral microvasculature and risk factors for cardiovascular disease at the Louisiana State University Health, in Shreveport, Louisiana, USA, from 2008 to 2011, and after that, from 2011 up to 2014, worked as a Pos-doc back at the University of Sao Paulo, this turn in the Faculty of Pharmaceutical Sciences, studing the therapeutical and toxicological effect of different nanoparticles in mice. Worked as a Young Investigator in the Institute of Biomedical Sciences (IBS) from the same University (University of Sao Paulo) from 2015 to 2019, and today works as assistant professor in the IBS-University of Sao Paulo. He studies the pharmacological effect of nanoparticles on brain disorders. HIs main interest areas are: microcirculation, nanomedicines, glioblastoma, ischemic stroke, and cerebral inflammation. He is a member of the Brazilian Society of Pharmacology and Experimental Therapeutic (SBFTE). e-mail address: stephen.rodrigues@usp.br (Source: Lattes Curriculum)
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Endothelial cells have a physiological role in maintaining hemostasis with antiplatelet, fibrinolytic, and antithrombotic effects. However, in pathological situations the endothelial phenotype can convert into a pro-thrombotic state with local and systemic consequences. The use of hydrogen sulfide (H2S), an important endogenous gaseous mediator, demonstrated antithrombotic and regulatory …
Coagulation is a complex phenomenon involving extra and intravascular, and extra and intracellular events that normally lead to thrombus formation and subsequent hemostasis, avoiding blood lost and death. However, this process needs to be carefully balanced to avoid disseminated thrombus formation, hypoxia, and tissue death. Thrombosis is one of the main causes of morbidity and mortality …
The acute respiratory distress syndrome (ARDS) is a disease that progresses quickly and is characterized mainly by pronounced lung edema and hypoxemia that lead to high morbidity and mortality rates. It is in great part caused by sepsis, pneumonia and, most recently, by the coronavirus disease 19 (COVID-19). Patients with ARDS require artificial ventilatory support in about 80% of the cas…
Although considered an immunoprivileged organ, the central nervous system (CNS) can still serve as scenario for different diseases. Among the more serious illnesses that affect the CNS are glioblastoma multiform and septic encephalopathy. These diseases own common features, mainly: inflammation and oxidative stress. Nanoparticles has come out as a new strategy for targeting diseases. As o…
Stroke and other diseases in which thrombus formation play an important role are the leading cause of morbidity and mortality from cardiovascular diseases. These conditions share a common feature, dysregulation of the blood coagulation process. Several studies report the involvement of divalent metal ions, such as zinc ion (Zn²¿), in modulating these pathways. Zn²¿ is secreted by active p…
Endothelial cells have a physiological role in maintaining hemostasis with antiplatelet, fibrinolytic, and antithrombotic effects. However, in pathological situations the endothelial phenotype can convert into a pro-thrombotic state with local and systemic consequences. The use of hydrogen sulfide (H2S), an important endogenous gaseous mediator, demonstrated antithrombotic and regulatory …
Nanotechnology is proving to be a very promising area, enabling new approaches with particularities capable of overcoming pre-existing limitations in various fields, generating optimistic expectations. This advance has contributed to the development of new products, including those intended for the maintenance of the health of individuals. In this context, nanoparticles (NPs), which are c…
Acute respiratory distress syndrome (ARDS) is a disease with rapid onset and is featured by an excessive acute inflammatory process in the lung, resulting in alveolar edema and subsequent tissue hypoxia. It is often observed in diseases like pneumonia, sepsis, and more recently, the coronavirus disease 19 (COVID-19). The pathogenesis of ARDS involves the neutrophils and monocytes traffick…
Semen quality has gained visibility as a biomarker of the men's global health. Several diseases change sperm quality and is observed in parallel that men with poor semen quality are in greater risk of dying the next years compared to men with good semen health. Among diseases that affect sperm, hypertension is highlighted due to its high prevalence; it is usually more severe in men, under…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 3 / 2 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 13 / 11 | Completed scholarships in Brazil |
| 20 / 17 | All research grants and scholarships |
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