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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Munira Muhammad Abdel Baqui in research grants and scholarships supported by FAPESP.
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Trypanosoma cruzi is a protozoan that causes Chagas Disease (CD), which is capable of invading almost any type of cell. At the beginning of infection, T. cruzi interacts with molecules on the surface of the host cell to adhere and penetrate and several changes in cellular metabolism and morphological changes occur in both cells. However, little is known about host nuclear organization dur…
We have demonstrated in all genera of Trypanosomatidae family the presence of high molecular mass proteins (1000-4000 kDa) associated to the cytoskeleton and that despite having variations in the biochemical and molecular properties, the, function of most of these giant proteins remains unknown and may be related to the life cycle and with the cellular adaptations of each organism. In add…
Over the past decades, the trypanosomatids have been used as experimental models for cellular, biochemical and molecular studies. They also represent an excellent model for cell biology suitable for investigation analysis of basic questions about the cytoskeleton and its evolution in higher eukaryotes (Gull 1999, 2003). In the Trypanosomatidae family, we demonstrated the existence of a ne…
Chagas' disease is caused by Trypanosoma cruzi and affects 8 million people, mostly in Latin America. In trypanosomatids, including T. cruzi, the presence of a giant protein (PGs) family with high molecular mass (e 500 kDa) has been demonstrated and located at the Flagellar Adhesion Zone (FAZ). This region has the function of connecting the cell body to the flagellum, playing numerous rol…
Trypanosoma brucei is a unicellular protozoa of great medical relevance since it is the etiological agent of sleeping sickness (African trypanosomiasis). Over the past decades, this organism has been used as experimental model for cellular, biochemical and molecular studies considering its particular structures as nucleus, cytoskeleton and the presence of unique organelles as kinetoplast …
| 1 / 1 | Ongoing grants |
| 4 / 3 | Completed research grants |
| 6 / 2 | Completed scholarships in Brazil |
| 11 / 6 | All research grants and scholarships |
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